Games like Wuppo: Definitive Edition
Games like Wuppo: Definitive Edition include Hollow Knight, Ori and the Will of the Wisps, Hollow Knight: Silksong, Dust: An Elysian Tail, and Celeste. We matched them by the tags players give Wuppo: Definitive Edition on Steam (Metroidvania, Exploration, Platformer, 2D, and 2D Platformer): closest matches first, and among equally close ones the better-known games.

Hollow Knight
Shared: Metroidvania · Platformer · 2D

Ori and the Will of the Wisps
Shared: Metroidvania · Platformer · Great Soundtrack

Hollow Knight: Silksong
Shared: Metroidvania · 2D · Great Soundtrack

Dust: An Elysian Tail
Shared: Metroidvania · Platformer · Action

Celeste
Shared: Platformer · Great Soundtrack · 2D Platformer

ANIMAL WELL
Shared: Metroidvania · Exploration · Platformer

Pizza Tower
Shared: 2D Platformer · Great Soundtrack · Platformer

Öoo
Shared: Metroidvania · Exploration · 2D Platformer

Webbed
Shared: 2D Platformer · Exploration · Cute

Cave Story+
Shared: Metroidvania · Exploration · Platformer

F.I.S.T.: Forged In Shadow Torch
Shared: Metroidvania · Platformer · 2D Platformer

OneShot
Shared: Cute · Great Soundtrack · Puzzle

The Messenger
Shared: Metroidvania · Platformer · 2D

Katana ZERO
Shared: Platformer · Great Soundtrack · Action

Bloodstained: Ritual of the Night
Shared: Metroidvania · Platformer · Action

UnEpic
Shared: Metroidvania · Platformer · Exploration

Portal 2
Shared: Platformer · Puzzle · Singleplayer

Momodora: Reverie Under The Moonlight
Shared: Metroidvania · Exploration · 2D Platformer

Rain World
Shared: Exploration · Platformer · 2D

Nine Sols
Shared: Metroidvania · 2D · Platformer

A Hat in Time
Shared: Cute · Great Soundtrack · Platformer

FEZ
Shared: Platformer · Exploration · Puzzle

Monster Boy and the Cursed Kingdom
Shared: Metroidvania · Platformer · 2D

Axiom Verge
Shared: Metroidvania · Platformer · 2D