Games like Wildemist Isle
Games like Wildemist Isle include Crimson Desert Enhanced, Slay the Spire 2, Slay the Spire, Vampire Crawlers: The Turbo Wildcard from Vampire Survivors, and Inscryption. We matched them by the tags players give Wildemist Isle on Steam (Card Battler, Open World, Exploration, Card Game, and Strategy): closest matches first, and among equally close ones the better-known games.

Crimson Desert Enhanced
Shared: Open World · Exploration · Fantasy

Slay the Spire 2
Shared: Card Game · Strategy · Card Battler

Slay the Spire
Shared: Card Battler · Card Game · Strategy

Vampire Crawlers: The Turbo Wildcard from Vampire Survivors
Shared: Card Battler · Strategy · Card Game

Inscryption
Shared: Card Battler · Card Game · Deckbuilding

Slime Rancher
Shared: Exploration · Open World · First-Person

Fallout 4
Shared: Open World · Exploration · First-Person

The Elder Scrolls IV: Oblivion Remastered
Shared: Open World · Exploration · Fantasy

Mount & Blade II: Bannerlord
Shared: Open World · Strategy · Medieval

The Elder Scrolls IV: Oblivion® Game of the Year Edition (2009)
Shared: Open World · Exploration · First-Person

Library Of Ruina
Shared: Card Game · Strategy · Deckbuilding

Mount & Blade: Warband
Shared: Open World · Strategy · Medieval

The Long Dark
Shared: Open World · Exploration · First-Person

Fallout: New Vegas
Shared: Open World · Exploration · First-Person

Hogwarts Legacy
Shared: Open World · Exploration · Fantasy

Balatro
Shared: Card Game · Strategy · Deckbuilding

Middle-earth: Shadow of War
Shared: Open World · Fantasy · Action

No Man's Sky
Shared: Open World · Exploration · First-Person

Kingdom Come: Deliverance II
Shared: Open World · First-Person · Medieval

The Forest
Shared: Open World · Exploration · First-Person

Grand Theft Auto V Legacy
Shared: Open World · First-Person · Action

DICEOMANCER
Shared: Card Battler · Card Game · Strategy

Far Cry® Primal
Shared: Open World · First-Person · Exploration

The Elder Scrolls Online - Standard Edition
Shared: Open World · Exploration · Fantasy