Games like Unity-Chan: Desktop Companion
Games like Unity-Chan: Desktop Companion include Chill with You : Lo-Fi Story, The Sims™ 4, Placid Plastic Duck Simulator, Paralives, and Unpacking. We matched them by the tags players give Unity-Chan: Desktop Companion on Steam (Dialogue Heavy, Female Protagonist, Relaxing, Utilities, and Cute): closest matches first, and among equally close ones the better-known games.

Chill with You : Lo-Fi Story
Shared: Relaxing · Utilities · Female Protagonist

The Sims™ 4
Shared: Life Sim · Character Customization · Relaxing

Placid Plastic Duck Simulator
Shared: Relaxing · Cute · Immersive Sim

Paralives
Shared: Life Sim · Character Customization · Relaxing

Unpacking
Shared: Relaxing · Cute · Casual

gogh: Focus with Your Avatar
Shared: Cute · Utilities · Relaxing

Youtubers Life 2
Shared: Life Sim · Character Customization · Female Protagonist

Stardew Valley
Shared: Relaxing · Life Sim · Simulation

Disney Dreamlight Valley
Shared: Relaxing · Life Sim · Character Customization

Slime Rancher 2
Shared: Relaxing · Cute · Female Protagonist

PowerWash Simulator
Shared: Relaxing · Casual · Simulation

Chill Pulse
Shared: Utilities · Cute · Casual

PC Building Simulator
Shared: Immersive Sim · Simulation · Relaxing

Calico
Shared: Cute · Relaxing · Female Protagonist

Desktop Kanojo
Shared: Female Protagonist · Software · Cute

On-Together: Virtual Co-Working
Shared: Utilities · Relaxing · Cute

Volcano Princess
Shared: Female Protagonist · Life Sim · Cute

My Dream Setup
Shared: Relaxing · Cute · Sandbox

Slime Rancher
Shared: Cute · Funny · Sandbox

Minami Lane
Shared: Cute · Relaxing · Life Sim

Little Witch in the Woods
Shared: Cute · Life Sim · Relaxing

inKONBINI: One Store. Many Stories
Shared: Dialogue Heavy · Relaxing · Female Protagonist

Coffee Talk
Shared: Dialogue Heavy · Relaxing · Interactive Fiction

inZOI
Shared: Life Sim · Character Customization · Simulation