Games like TowerDefenceDesigner
Games like TowerDefenceDesigner include Creeper World 3: Arc Eternal, Creeper World 4, This War of Mine, Command & Conquer™ Remastered Collection, and Command & Conquer™ Red Alert™ 3. We matched them by the tags players give TowerDefenceDesigner on Steam (Tower Defense, Base Building, 3D Platformer, Space, and War): closest matches first, and among equally close ones the better-known games.

Creeper World 3: Arc Eternal
Shared: Tower Defense · Strategy · Level Editor

Creeper World 4
Shared: Tower Defense · Space · RTS

This War of Mine
Shared: War · Base Building · Strategy

Command & Conquer™ Remastered Collection
Shared: Base Building · Strategy · War

Command & Conquer™ Red Alert™ 3
Shared: Level Editor · Base Building · Strategy

Outpost: Infinity Siege
Shared: Tower Defense · Base Building · Robots

Planetary Annihilation: TITANS
Shared: Base Building · Strategy · RTS

Taur
Shared: Tower Defense · Base Building · Strategy

Age of Mythology: Retold
Shared: Base Building · Strategy · RTS

Age of Empires III: Definitive Edition
Shared: Base Building · Strategy · RTS

They Are Billions
Shared: Base Building · Tower Defense · Strategy

The Riftbreaker
Shared: Base Building · Tower Defense · Crafting

Mindustry
Shared: Tower Defense · Base Building · Strategy

Command & Conquer 3 Tiberium Wars™
Shared: Level Editor · Strategy · Base Building

Dyson Sphere Program
Shared: Base Building · Space · Simulation

Bloons TD 6
Shared: Tower Defense · Strategy · Casual

Warpips
Shared: Tower Defense · War · Strategy

Age of Darkness: Final Stand
Shared: Tower Defense · Base Building · Strategy

Tower Dominion
Shared: Tower Defense · Base Building · Strategy

Tempest Rising
Shared: Base Building · Strategy · RTS

Command & Conquer: Red Alert 3 - Uprising
Shared: Level Editor · Strategy · Base Building

Factorio
Shared: Base Building · Crafting · Strategy

Rogue Tower
Shared: Tower Defense · Base Building · Strategy

STAR WARS™ Empire at War - Gold Pack
Shared: Space · Strategy · RTS