Games like Tower 57
Games like Tower 57 include Broforce, Hotline Miami, Hotline Miami 2: Wrong Number, Nuclear Throne, and Enter the Gungeon. We matched them by the tags players give Tower 57 on Steam (Action, Indie, Pixel Graphics, Top-Down Shooter, and Dystopian ): closest matches first, and among equally close ones the better-known games.

Broforce
Shared: Action · Pixel Graphics · Indie

Hotline Miami
Shared: Action · Indie · Pixel Graphics

Hotline Miami 2: Wrong Number
Shared: Pixel Graphics · Action · Great Soundtrack

Nuclear Throne
Shared: Pixel Graphics · Indie · Action

Enter the Gungeon
Shared: Pixel Graphics · Indie · Local Co-Op

Duck Game
Shared: Action · Pixel Graphics · Indie

Cuphead
Shared: Local Co-Op · Indie · Great Soundtrack

Katana ZERO
Shared: Action · Pixel Graphics · Indie

HELLDIVERS™ Dive Harder Edition
Shared: Top-Down Shooter · Action · Local Co-Op

Shovel Knight: Treasure Trove
Shared: Pixel Graphics · Indie · Action

Relic Hunters Zero: Remix
Shared: Action · Top-Down Shooter · Twin Stick Shooter

Risk of Rain (2013)
Shared: Indie · Action · Pixel Graphics

Door Kickers: Action Squad
Shared: Pixel Graphics · Action · Local Co-Op

RUINER
Shared: Action · Top-Down Shooter · Indie

Streets of Rage 4
Shared: Action · Indie · 2D

The Ascent
Shared: Top-Down Shooter · Action · Indie

The Binding of Isaac: Rebirth
Shared: Indie · Pixel Graphics · Great Soundtrack

UFO 50
Shared: Indie · Pixel Graphics · Action

UBERMOSH
Shared: Action · Pixel Graphics · Indie

SYNTHETIK: Legion Rising
Shared: Indie · Action · Top-Down Shooter

Hyper Light Drifter
Shared: Pixel Graphics · Indie · Action

Mother Russia Bleeds
Shared: Action · Pixel Graphics · Indie

Papers, Please
Shared: Indie · Pixel Graphics · Dystopian

Rivals of Aether
Shared: Pixel Graphics · Indie · Action