Games like The Room Syndrome
Games like The Room Syndrome include Poppy Playtime, OneShot, Please, Don’t Touch Anything, Pony Island, and Samsara Room. We matched them by the tags players give The Room Syndrome on Steam (Free to Play, Indie, Casual, Puzzle, and Psychological Horror): closest matches first, and among equally close ones the better-known games.

Poppy Playtime
Shared: Free to Play · Puzzle · Psychological Horror

OneShot
Shared: Indie · Pixel Graphics · Puzzle

Please, Don’t Touch Anything
Shared: Indie · Puzzle · Pixel Graphics

Pony Island
Shared: Indie · Puzzle · Psychological Horror

Samsara Room
Shared: Indie · Free to Play · Puzzle

Undertale
Shared: Pixel Graphics · Multiple Endings · Choices Matter

DISTRAINT: Deluxe Edition
Shared: Indie · Psychological Horror · Pixel Graphics

OMORI
Shared: Indie · Psychological Horror · Pixel Graphics

Papers, Please
Shared: Indie · Pixel Graphics · Puzzle

Outcore: Desktop Adventure
Shared: Psychological Horror · Free to Play · Puzzle

Assemble with Care
Shared: Indie · Casual · Puzzle

No, I'm not a Human
Shared: Indie · Psychological Horror · Choices Matter

Ib
Shared: Indie · Pixel Graphics · Psychological Horror

We Were Here
Shared: Free to Play · Puzzle · Psychological Horror

Martial Law
Shared: Free to Play · Pixel Graphics · Indie

Emily is Away Too
Shared: Indie · Casual · Choices Matter

Milk outside a bag of milk outside a bag of milk
Shared: Psychological Horror · Indie · Pixel Graphics

There Is No Game: Wrong Dimension
Shared: Indie · Puzzle · Pixel Graphics

Death and Taxes
Shared: Psychological Horror · Choices Matter · Multiple Endings

Zup! S
Shared: Indie · Casual · Puzzle

Unpacking
Shared: Casual · Puzzle · Pixel Graphics

Donut County
Shared: Indie · Casual · Puzzle

Little Misfortune
Shared: Indie · Psychological Horror · Choices Matter

Zup!
Shared: Indie · Casual · Puzzle