Games like The Fermi Paradox
Games like The Fermi Paradox include FTL: Faster Than Light, Star Trek: Voyager - Across the Unknown, Cosmoteer: Starship Architect & Commander, Death and Taxes, and Undertale. We matched them by the tags players give The Fermi Paradox on Steam (God Game, Space Sim, Choices Matter, Sci-fi, and Indie): closest matches first, and among equally close ones the better-known games.

FTL: Faster Than Light
Shared: Sci-fi · Indie · Strategy

Star Trek: Voyager - Across the Unknown
Shared: Space Sim · Strategy · Interactive Fiction

Cosmoteer: Starship Architect & Commander
Shared: Sci-fi · Space Sim · Indie

Death and Taxes
Shared: Choices Matter · Strategy · Multiple Endings

Undertale
Shared: Choices Matter · Multiple Endings · Indie

Detroit: Become Human
Shared: Choices Matter · Multiple Endings · Sci-fi

Beholder
Shared: Choices Matter · Strategy · Indie

Reus
Shared: God Game · Indie · Strategy

Dyson Sphere Program
Shared: Sci-fi · Resource Management · Space

Late Shift
Shared: Choices Matter · Interactive Fiction · Indie

SPORE™
Shared: God Game · Sci-fi · Aliens

Kerbal Space Program
Shared: Space Sim · Space · Indie

This War of Mine
Shared: Choices Matter · Strategy · Resource Management

Universe Sandbox
Shared: Space Sim · God Game · Space

The Life and Suffering of Sir Brante
Shared: Choices Matter · Interactive Fiction · Indie

Elite Dangerous
Shared: Space Sim · Sci-fi · Space

Oxygen Not Included
Shared: Resource Management · Strategy · 2D

Hardspace: Shipbreaker
Shared: Sci-fi · Space Sim · Space

Papers, Please
Shared: Indie · Multiple Endings · Simulation

The Universim
Shared: God Game · Strategy · Indie

The Henry Stickmin Collection
Shared: Choices Matter · Multiple Endings · Choose Your Own Adventure

Yes, Your Grace
Shared: Choices Matter · Indie · Multiple Endings

Aliya: Timelink
Shared: Interactive Fiction · Sci-fi · Multiple Endings

X4: Foundations
Shared: Space Sim · Sci-fi · Space