Games like The Crafter's Defense
Games like The Crafter's Defense include Creeper World 4, Thronefall, Factorio, Artisan TD, and shapez 2 - Factory. We matched them by the tags players give The Crafter's Defense on Steam (Mystery Dungeon, Tower Defense, Dungeon Crawler, Real Time Tactics, and Building): closest matches first, and among equally close ones the better-known games.

Creeper World 4
Shared: Tower Defense · Real Time Tactics · Building

Thronefall
Shared: Tower Defense · Strategy · Building

Factorio
Shared: Automation · Crafting · Strategy

Artisan TD
Shared: Tower Defense · Building · Strategy

shapez 2 - Factory
Shared: Building · Automation · Strategy

Mindustry
Shared: Tower Defense · Automation · Building

Bloons TD 6
Shared: Tower Defense · Strategy · 3D

Satisfactory
Shared: Automation · Crafting · Building

DG2: Defense Grid 2
Shared: Tower Defense · Strategy · Real Time Tactics

Schedule I
Shared: Crafting · Simulation · Automation

Dyson Sphere Program
Shared: Automation · Building · Simulation

MineMogul
Shared: Building · Automation · Crafting

Kingdom Two Crowns
Shared: Tower Defense · Building · Strategy

Little Big Workshop
Shared: Building · Strategy · Automation

shapez
Shared: Automation · Crafting · Strategy

Kingdom Rush Origins - Tower Defense
Shared: Tower Defense · Strategy · Building

Kingdom Rush 5: Alliance TD
Shared: Tower Defense · Strategy · Building

Dungeon Defenders
Shared: Tower Defense · Strategy · Building

Element TD 2 - Tower Defense
Shared: Tower Defense · Real Time Tactics · Strategy

Age of Darkness: Final Stand
Shared: Tower Defense · Strategy · 3D

Planet Coaster
Shared: Building · Strategy · Simulation

Orcs Must Die! 3
Shared: Tower Defense · Strategy · Action

Tavern Master
Shared: Building · Strategy · Simulation

Stronghold Crusader: Definitive Edition
Shared: Real Time Tactics · Strategy · Building