Games like Take A Leak
Games like Take A Leak include Portal, The Henry Stickmin Collection, Poppy Playtime, Human Fall Flat, and The Room. We matched them by the tags players give Take A Leak on Steam (Comedy, Puzzle, Physics, Multiple Endings, and Mystery): closest matches first, and among equally close ones the better-known games.

Portal
Shared: Puzzle · Comedy · Physics

The Henry Stickmin Collection
Shared: Multiple Endings · Comedy · Funny

Poppy Playtime
Shared: Puzzle · Singleplayer · Horror

Human Fall Flat
Shared: Puzzle · Physics · Funny

The Room
Shared: Puzzle · Mystery · Singleplayer

The Stanley Parable
Shared: Comedy · Funny · Multiple Endings

Garry's Mod
Shared: Physics · Funny · Comedy

Firewatch
Shared: Mystery · Adventure · Singleplayer

Portal 2
Shared: Puzzle · Singleplayer · Funny

Goat Simulator
Shared: Comedy · Physics · Funny

Donut County
Shared: Puzzle · Physics · Funny

The Room Two
Shared: Puzzle · Mystery · Horror

The Room Three
Shared: Puzzle · Mystery · Singleplayer

Return of the Obra Dinn
Shared: Puzzle · Mystery · Singleplayer

Toilet Chronicles
Shared: Comedy · Multiple Endings · Funny

There Is No Game: Wrong Dimension
Shared: Puzzle · Comedy · Funny

Getting Over It with Bennett Foddy
Shared: Physics · Singleplayer · Funny

WHAT THE GOLF?
Shared: Comedy · Physics · Memes

World of Goo
Shared: Puzzle · Physics · Comedy

Little Inferno
Shared: Puzzle · Comedy · Funny

Bendy and the Ink Machine
Shared: Puzzle · Horror · Singleplayer

Octodad: Dadliest Catch
Shared: Comedy · Physics · Funny

R.E.P.O.
Shared: Comedy · Physics · Horror

Superliminal
Shared: Puzzle · Physics · Singleplayer