Games like Substrate: Emergence
Games like Substrate: Emergence include SPORE™, WorldBox - God Simulator, Prison Architect, RimWorld, and Oxygen Not Included. We matched them by the tags players give Substrate: Emergence on Steam (Exploration, Creature Collector, Roguelite, Colony Sim, and Sandbox): closest matches first, and among equally close ones the better-known games.
SPORE™
Shared: Exploration · God Game · Colony Sim
WorldBox - God Simulator
Shared: Sandbox · God Game · Colony Sim
Prison Architect
Shared: Sandbox · Colony Sim · Simulation
RimWorld
Shared: Colony Sim · Sandbox · Strategy
Oxygen Not Included
Shared: Colony Sim · Sandbox · 2D
Stardeus
Shared: Exploration · Colony Sim · Sandbox
Ultimate Epic Battle Simulator 2
Shared: Sandbox · God Game · Simulation
Kerbal Space Program
Shared: Sandbox · Simulation · Exploration
Spaceflight Simulator
Shared: Sandbox · Exploration · Simulation
Kingdoms and Castles
Shared: Colony Sim · Sandbox · Strategy
The Universim
Shared: Colony Sim · Sandbox · God Game
The Wandering Village
Shared: Exploration · Colony Sim · Simulation
Banished
Shared: Colony Sim · Strategy · Sandbox
Anno 117: Pax Romana
Shared: Sandbox · Strategy · Exploration
Drill Core
Shared: Roguelite · Exploration · Colony Sim
Dwarf Fortress
Shared: Colony Sim · Sandbox · Strategy
Slime Rancher
Shared: Exploration · Cute · Sandbox
Stonehearth
Shared: Colony Sim · Sandbox · Strategy
Terraria
Shared: Sandbox · Exploration · 2D
Universe Sandbox
Shared: Sandbox · Simulation · God Game
Settlement Survival
Shared: Colony Sim · Exploration · Sandbox
Craft The World
Shared: Colony Sim · Sandbox · Strategy
Planetary Life
Shared: Sandbox · God Game · Simulation
Totally Accurate Battle Simulator
Shared: Sandbox · Simulation · Strategy