Games like Struggle F.O
Games like Struggle F.O include Vampire Survivors, Hades II, Hades, Skul: The Hero Slayer, and Brotato. We matched them by the tags players give Struggle F.O on Steam (Action, Casual, Dinosaurs, Sci-fi, and Roguelike): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: Action Roguelike · Casual · Roguelike

Hades II
Shared: Action · Roguelike · Action Roguelike

Hades
Shared: Action · Action Roguelike · Roguelike

Skul: The Hero Slayer
Shared: Action · Roguelike · Action Roguelike

Brotato
Shared: Roguelike · Action Roguelike · Singleplayer

Rogue Legacy
Shared: Action · Roguelike · Action Roguelike

Megabonk
Shared: Roguelike · Action Roguelike · Action

Juicy Realm
Shared: Action · Casual · RPG

The Binding of Isaac
Shared: Roguelike · Action Roguelike · Action

ICEY
Shared: Action · RPG · Singleplayer

Death Must Die
Shared: Action Roguelike · Action · RPG

Cat Quest
Shared: Action · RPG · Casual

BioShock Infinite
Shared: Action · RPG · Singleplayer

The Binding of Isaac: Rebirth
Shared: Roguelike · Action Roguelike · Indie

Dungreed
Shared: Action · Roguelike · Action Roguelike

Dead Cells
Shared: Roguelike · Action Roguelike · Adventure

ORION: Prelude
Shared: Action · Dinosaurs · Sci-fi

Sephiria
Shared: Roguelike · Action · Action Roguelike

Ravenswatch
Shared: Action · Roguelike · Action Roguelike

Dragon's Dogma 2
Shared: Action · RPG · Singleplayer

Hand of Fate
Shared: Roguelike · Action · RPG

Crimson Desert Enhanced
Shared: Action · Singleplayer · RPG

Boneraiser Minions
Shared: Action Roguelike · Casual · Action

UnderMine
Shared: Action · Action Roguelike · RPG