Games like Star Trek: Infinite
Games like Star Trek: Infinite include Stellaris, Sins of a Solar Empire®: Rebellion, X4: Foundations, Europa Universalis IV, and Galactic Civilizations IV. We matched them by the tags players give Star Trek: Infinite on Steam (Grand Strategy, 4X, Space, Exploration, and Sandbox): closest matches first, and among equally close ones the better-known games.
Stellaris
Shared: Grand Strategy · Space · 4X
Sins of a Solar Empire®: Rebellion
Shared: Management · Space · Diplomacy
X4: Foundations
Shared: Space · Exploration · 4X
Europa Universalis IV
Shared: Grand Strategy · 4X · Diplomacy
Galactic Civilizations IV
Shared: Grand Strategy · Space · 4X
Crusader Kings III
Shared: Grand Strategy · Management · Sandbox
Avorion
Shared: Exploration · Sandbox · Space
Kerbal Space Program
Shared: Space · Sandbox · Simulation
EVE Online
Shared: Exploration · Space · Space Sim
Terra Invicta
Shared: Grand Strategy · 4X · Management
No Man's Sky
Shared: Space · Exploration · Sandbox
Rebel Inc: Escalation
Shared: Grand Strategy · 4X · Management
Kerbal Space Program 2
Shared: Space · Exploration · Sandbox
Elite Dangerous
Shared: Space · Exploration · Space Sim
SPORE™
Shared: Sandbox · Exploration · Space
Manor Lords
Shared: Grand Strategy · Management · Sandbox
NEBULOUS: Fleet Command
Shared: Grand Strategy · 4X · RTS
Sid Meier's Civilization VII
Shared: Grand Strategy · 4X · Diplomacy
Dune: Spice Wars
Shared: Management · 4X · Grand Strategy
Knights of Honor II: Sovereign
Shared: Grand Strategy · 4X · RTS
Hearts of Iron IV
Shared: Grand Strategy · Strategy · RTS
Sins of a Solar Empire II
Shared: Space · 4X · RTS
Sid Meier’s Civilization® VI
Shared: Grand Strategy · 4X · Strategy
Galactic Civilizations III
Shared: 4X · Grand Strategy · Sandbox