Games like Spaceflight Factory : Prologue
Games like Spaceflight Factory : Prologue include Dyson Sphere Program, Timberborn, Factorio, Manor Lords, and Captain of Industry. We matched them by the tags players give Spaceflight Factory : Prologue on Steam (Simulation, Base Building, Strategy, City Builder, and Automation): closest matches first, and among equally close ones the better-known games.

Dyson Sphere Program
Shared: Base Building · Automation · Simulation

Timberborn
Shared: City Builder · Automation · Base Building

Factorio
Shared: Base Building · Automation · Strategy

Manor Lords
Shared: Simulation · Strategy · Base Building

Captain of Industry
Shared: Base Building · Simulation · Automation

shapez 2 - Factory
Shared: Automation · Strategy · Simulation

Against the Storm
Shared: Simulation · Strategy · Base Building

Cities: Skylines
Shared: Simulation · City Builder · Strategy

Workers & Resources: Soviet Republic
Shared: Simulation · Strategy · Base Building

MineMogul
Shared: Automation · Strategy · Simulation

Prison Architect
Shared: Simulation · Base Building · Strategy

Totally Accurate Battle Simulator
Shared: Simulation · Strategy · Physics

Planetbase
Shared: Base Building · City Builder · Strategy

Empires of the Undergrowth
Shared: Simulation · Strategy · Base Building

Dwarf Fortress
Shared: Base Building · Simulation · Strategy

RimWorld
Shared: Base Building · Strategy · Simulation

Beltmatic
Shared: Base Building · Automation · Simulation

Infection Free Zone
Shared: Base Building · City Builder · Strategy

IXION
Shared: Strategy · City Builder · Base Building

Going Medieval
Shared: Base Building · Strategy · City Builder

Automation Empire
Shared: Simulation · Strategy · Base Building

Space Engineers
Shared: Simulation · Base Building · Physics

shapez
Shared: Base Building · Automation · Strategy

Mini Motorways
Shared: Simulation · Strategy · Casual