Games like Space Sprouts
Games like Space Sprouts include Kerbal Space Program, People Playground, Spaceflight Simulator, Kerbal Space Program 2, and Hollow Knight. We matched them by the tags players give Space Sprouts on Steam (Exploration, Puzzle, Physics, Simulation, and Metroidvania): closest matches first, and among equally close ones the better-known games.

Kerbal Space Program
Shared: Simulation · Physics · Sandbox

People Playground
Shared: Physics · Sandbox · 2D

Spaceflight Simulator
Shared: Exploration · Sandbox · Simulation

Kerbal Space Program 2
Shared: Exploration · Physics · Sandbox

Hollow Knight
Shared: Metroidvania · Exploration · 2D

Hollow Knight: Silksong
Shared: Metroidvania · Exploration · 2D

Hardspace: Shipbreaker
Shared: Physics · Simulation · Puzzle

Garry's Mod
Shared: Physics · Sandbox · Simulation

Totally Accurate Battle Simulator
Shared: Simulation · Sandbox · Physics

Bridge Constructor Portal
Shared: Puzzle · Simulation · Physics

ANIMAL WELL
Shared: Exploration · Puzzle · Metroidvania

Slime Rancher
Shared: Exploration · Simulation · Sandbox

Supraland
Shared: Exploration · Metroidvania · Physics

Poly Bridge
Shared: Physics · Puzzle · Simulation

鬼谷八荒 Tale of Immortal
Shared: Simulation · Sandbox · Singleplayer

Elite Dangerous
Shared: Exploration · Simulation · Space Sim

Space Engineers
Shared: Sandbox · Simulation · Physics

Universe Sandbox
Shared: Simulation · Physics · Sandbox

Empyrion - Galactic Survival
Shared: Simulation · Exploration · Sandbox

Human Fall Flat
Shared: Puzzle · Physics · Sandbox

Goat Simulator 3
Shared: Exploration · Physics · Sandbox

BONEWORKS
Shared: Physics · Sandbox · Puzzle

Crazy Machines 3
Shared: Puzzle · Simulation · Physics

Terraria
Shared: Sandbox · 2D · Exploration