Games like Space Raiders in Space
Games like Space Raiders in Space include Hades, FTL: Faster Than Light, The Binding of Isaac, The Binding of Isaac: Rebirth, and Skul: The Hero Slayer. We matched them by the tags players give Space Raiders in Space on Steam (Strategy, Indie, Action, Comic Book, and Roguelike): closest matches first, and among equally close ones the better-known games.

Hades
Shared: Indie · Action · Roguelite

FTL: Faster Than Light
Shared: Strategy · Roguelike · Indie

The Binding of Isaac
Shared: Indie · Roguelike · Action

The Binding of Isaac: Rebirth
Shared: Indie · Roguelike · Replay Value

Skul: The Hero Slayer
Shared: Indie · Action · Roguelike

Megabonk
Shared: Indie · Roguelike · Action

Octogeddon
Shared: Action · Indie · Strategy

Cluckmech Oasis
Shared: Strategy · Roguelike · Tower Defense

Dungeon of the ENDLESS™
Shared: Strategy · Roguelike · Indie

Hades II
Shared: Action · Roguelike · Roguelite

Balatro
Shared: Roguelike · Strategy · Indie

Gunfire Reborn
Shared: Roguelike · Indie · Roguelite

Heat Signature
Shared: Indie · Strategy · Action

Infested Planet
Shared: Strategy · Action · Indie

Orcs Must Die!
Shared: Strategy · Action · Tower Defense

Defense Grid: The Awakening
Shared: Strategy · Indie · Tower Defense

Vampire Survivors
Shared: Indie · Roguelite · Action Roguelike

X-Morph: Defense
Shared: Strategy · Action · Indie

Ravenswatch
Shared: Roguelike · Action · Indie

Streets of Rogue
Shared: Action · Indie · Roguelike

Risk of Rain 2
Shared: Roguelike · Action · Action Roguelike

Slay the Spire
Shared: Strategy · Roguelike · Indie

Wall World
Shared: Strategy · Roguelike · Tower Defense

The King is Watching
Shared: Roguelike · Strategy · Tower Defense