Games like Slayin 2
Games like Slayin 2 include Hero Siege, Broforce, Streets of Rage 4, UFO 50, and Vampire Survivors. We matched them by the tags players give Slayin 2 on Steam (Action RPG, Arcade, Hack and Slash, Colorful, and Pixel Graphics): closest matches first, and among equally close ones the better-known games.

Hero Siege
Shared: Action RPG · Hack and Slash · Pixel Graphics

Broforce
Shared: Pixel Graphics · 2D · Local Co-Op

Streets of Rage 4
Shared: Arcade · 2D · Local Multiplayer

UFO 50
Shared: Pixel Graphics · Arcade · 2D

Vampire Survivors
Shared: Pixel Graphics · 2D · Arcade

Castle Crashers®
Shared: 2D · Hack and Slash · Local Co-Op

Chronicon
Shared: Action RPG · Hack and Slash · Pixel Graphics

Halls of Torment
Shared: Action RPG · Pixel Graphics · Arcade

Teenage Mutant Ninja Turtles: Shredder's Revenge
Shared: Pixel Graphics · Arcade · 2D

Sonic Mania
Shared: 2D · Pixel Graphics · Colorful

METAL SLUG
Shared: Arcade · 2D · Action

The Slormancer
Shared: Hack and Slash · Action RPG · Pixel Graphics

Shovel Knight: Treasure Trove
Shared: Pixel Graphics · 2D · Indie

Huntdown
Shared: Pixel Graphics · Local Co-Op · 2D

The Mageseeker: A League of Legends Story™
Shared: Hack and Slash · Pixel Graphics · 2D

Last Epoch
Shared: Action RPG · Hack and Slash · Action

Children of Morta
Shared: Hack and Slash · Pixel Graphics · Local Co-Op

Wolcen: Lords of Mayhem
Shared: Action RPG · Hack and Slash · Action

Mighty Morphin Power Rangers: Rita's Rewind
Shared: Arcade · Pixel Graphics · 2D

MARVEL Cosmic Invasion
Shared: Arcade · Pixel Graphics · 2D

Fight'N Rage
Shared: 2D · Arcade · Local Co-Op

Duck Game
Shared: Pixel Graphics · Local Multiplayer · 2D

Rhythm Doctor
Shared: Pixel Graphics · Local Co-Op · 2D

Nobody Saves the World
Shared: Hack and Slash · Action RPG · 2D