Games like Senalux
Games like Senalux include Baba Is You, Opus Magnum, SpaceChem, Hexcells, and Hexcells Infinite. We matched them by the tags players give Senalux on Steam (Puzzle, Indie, Difficult, Logic, and Hex Grid): closest matches first, and among equally close ones the better-known games.

Baba Is You
Shared: Puzzle · Indie · Difficult

Opus Magnum
Shared: Puzzle · Indie · Logic

SpaceChem
Shared: Puzzle · Difficult · Indie

Hexcells
Shared: Puzzle · Indie · Logic

Hexcells Infinite
Shared: Puzzle · Indie · Logic

Zup! S
Shared: Puzzle · Indie · Casual

Patrick's Parabox
Shared: Puzzle · Logic · Indie

Human Resource Machine
Shared: Puzzle · Indie · Programming

LYNE
Shared: Puzzle · Logic · Difficult

Hexcells Plus
Shared: Puzzle · Indie · Logic

while True: learn()
Shared: Puzzle · Indie · Simulation

TIS-100
Shared: Puzzle · Indie · Difficult

Mini Metro
Shared: Puzzle · Indie · Simulation

SHENZHEN I/O
Shared: Puzzle · Logic · Difficult

Poly Bridge
Shared: Puzzle · Simulation · Difficult

Bridge Constructor Portal
Shared: Puzzle · Simulation · Difficult

Papers, Please
Shared: Indie · Simulation · Puzzle

Hook
Shared: Puzzle · Indie · Casual

7 Billion Humans
Shared: Puzzle · Indie · Simulation

Infinifactory
Shared: Puzzle · Indie · Difficult

Game Dev Tycoon
Shared: Indie · Simulation · Singleplayer

Kerbal Space Program
Shared: Simulation · Indie · Science

Poly Bridge 2
Shared: Puzzle · Difficult · Simulation

Mini Motorways
Shared: Puzzle · Simulation · Indie