Games like Science Girls
Games like Science Girls include Hyperdimension Neptunia Re;Birth1, Mirror 2: Project X, Digimon Story Cyber Sleuth: Complete Edition, Persona 5 Royal, and Persona 4 Golden. We matched them by the tags players give Science Girls on Steam (JRPG, Female Protagonist, Science, Anime, and Sci-fi): closest matches first, and among equally close ones the better-known games.

Hyperdimension Neptunia Re;Birth1
Shared: JRPG · Female Protagonist · Anime

Mirror 2: Project X
Shared: Female Protagonist · Anime · Visual Novel

Digimon Story Cyber Sleuth: Complete Edition
Shared: JRPG · Anime · RPG

Persona 5 Royal
Shared: JRPG · Anime · RPG

Persona 4 Golden
Shared: JRPG · Anime · RPG

Volcano Princess
Shared: Female Protagonist · RPG · Anime

FINAL FANTASY X/X-2 HD Remaster
Shared: JRPG · RPG · Turn-Based Combat

Persona 3 Portable
Shared: JRPG · RPG · Female Protagonist

Hyperdimension Neptunia Re;Birth2: Sisters Generation
Shared: JRPG · Female Protagonist · Anime

NieR:Automata™
Shared: Female Protagonist · RPG · JRPG

FINAL FANTASY® XIII
Shared: JRPG · Female Protagonist · RPG

Atelier Sophie 2: The Alchemist of the Mysterious Dream
Shared: JRPG · Female Protagonist · Anime

Hyperdimension Neptunia Re;Birth3 V Generation
Shared: JRPG · Female Protagonist · Anime

The Legend of Heroes: Trails in the Sky
Shared: JRPG · Anime · RPG

Path Of Wuxia
Shared: RPG · Indie · Female Protagonist

Tales of Berseria™
Shared: JRPG · Anime · Female Protagonist

FINAL FANTASY® XIII-2
Shared: JRPG · Female Protagonist · RPG

WitchSpring R
Shared: Female Protagonist · JRPG · RPG

Banner of the Maid
Shared: Female Protagonist · RPG · JRPG

Metaphor: ReFantazio
Shared: JRPG · RPG · Anime

Tales of the Black Forest
Shared: RPG · Female Protagonist · Indie

Megadimension Neptunia VII
Shared: JRPG · Female Protagonist · Anime

Persona 3 Reload
Shared: JRPG · Anime · RPG

The Legend of Heroes: Trails in the Sky SC
Shared: JRPG · Anime · RPG