Games like Save the Reactor
Games like Save the Reactor include Papers, Please, Rain World, Hollow Knight, Touhou Mystia's Izakaya, and Digseum. We matched them by the tags players give Save the Reactor on Steam (Simulation, Difficult, Pixel Graphics, Point & Click, and Time Management): closest matches first, and among equally close ones the better-known games.

Papers, Please
Shared: Simulation · Pixel Graphics · Point & Click

Rain World
Shared: Difficult · Pixel Graphics · Atmospheric

Hollow Knight
Shared: Difficult · Souls-like · 2D

Touhou Mystia's Izakaya
Shared: Simulation · Pixel Graphics · Time Management

Digseum
Shared: Simulation · Incremental · Pixel Graphics

Cookie Clicker
Shared: Incremental · Pixel Graphics · Management

Lobotomy Corporation | Monster Management Simulation
Shared: Difficult · Simulation · Management

Hollow Knight: Silksong
Shared: Difficult · Souls-like · 2D

Punch Club
Shared: Pixel Graphics · Time Management · Simulation

Do Not Feed the Monkeys
Shared: Point & Click · Management · Pixel Graphics

Game Dev Tycoon
Shared: Simulation · Management · Indie

Click the Button
Shared: Simulation · Pixel Graphics · Incremental

The Escapists
Shared: Pixel Graphics · Simulation · Difficult

Noita
Shared: Pixel Graphics · Difficult · Simulation

Graveyard Keeper
Shared: Pixel Graphics · Simulation · Management

Stardew Valley
Shared: Pixel Graphics · Simulation · Life Sim

Celeste
Shared: Difficult · Pixel Graphics · Indie

Blasphemous
Shared: Pixel Graphics · Difficult · Souls-like

Titan Souls
Shared: Difficult · Pixel Graphics · Souls-like

Please, Don’t Touch Anything
Shared: Pixel Graphics · Point & Click · Multiple Endings

The Binding of Isaac: Rebirth
Shared: Difficult · Pixel Graphics · Indie

Shelldiver
Shared: Incremental · Simulation · Management

Hyper Light Drifter
Shared: Pixel Graphics · Difficult · Atmospheric

Nodebuster
Shared: Simulation · Incremental · Management