Games like Savage Vessels
Games like Savage Vessels include Heat Signature, Skul: The Hero Slayer, SYNTHETIK: Legion Rising, Nuclear Throne, and FTL: Faster Than Light. We matched them by the tags players give Savage Vessels on Steam (Action, Indie, Space, Top-Down Shooter, and Roguelike): closest matches first, and among equally close ones the better-known games.

Heat Signature
Shared: Space · Indie · Action

Skul: The Hero Slayer
Shared: Action · Indie · Roguelike

SYNTHETIK: Legion Rising
Shared: Indie · Action · Top-Down Shooter

Nuclear Throne
Shared: Indie · Roguelike · Action

FTL: Faster Than Light
Shared: Space · Roguelike · Indie

Hades
Shared: Indie · Action · Roguelike

EVERSPACE™
Shared: Action · Space · Indie

Hades II
Shared: Action · Roguelike · Indie

The Binding of Isaac
Shared: Indie · Roguelike · Action

Risk of Rain (2013)
Shared: Indie · Action · Roguelike

Megabonk
Shared: Indie · Roguelike · Action

BALL x PIT
Shared: Action · Roguelike · Top-Down Shooter

Rogue Legacy
Shared: Indie · Action · Roguelike

Dome Keeper
Shared: Action · Roguelike · Space

Deliver Us The Moon
Shared: Indie · Action · Space

RUINER
Shared: Action · Top-Down Shooter · Indie

Hotline Miami
Shared: Action · Indie · Top-Down Shooter

Trailmakers
Shared: Action · Space · Indie

Gunfire Reborn
Shared: Roguelike · Indie · Action

The Binding of Isaac: Rebirth
Shared: Indie · Roguelike · Action

The Ascent
Shared: Top-Down Shooter · Action · Indie

Starcom: Unknown Space
Shared: Space · Top-Down Shooter · Indie

Star Valor
Shared: Action · Space · Top-Down Shooter

Chorus
Shared: Action · Indie · Space