Games like Sanctum 2
Games like Sanctum 2 include Counter-Strike 2, PUBG: BATTLEGROUNDS, Left 4 Dead 2, PAYDAY 2, and Starship Troopers: Extermination. We matched them by the tags players give Sanctum 2 on Steam (Tower Defense, FPS, Strategy, Action, and Sci-fi): closest matches first, and among equally close ones the better-known games.

Counter-Strike 2
Shared: FPS · Action · Multiplayer

PUBG: BATTLEGROUNDS
Shared: FPS · Action · Multiplayer

Left 4 Dead 2
Shared: FPS · Co-op · Action

PAYDAY 2
Shared: Co-op · FPS · Action

Starship Troopers: Extermination
Shared: FPS · Action · Online Co-Op

Bloons TD 6
Shared: Tower Defense · Strategy · Co-op

Call of Duty®: Black Ops III
Shared: FPS · Action · Multiplayer

Sanctum
Shared: Tower Defense · FPS · Co-op

Tom Clancy's Rainbow Six Siege
Shared: FPS · Multiplayer · Action

Call of Duty®
Shared: FPS · Action · Multiplayer

Halo Infinite
Shared: FPS · Action · Multiplayer

STAR WARS™ Battlefront™ II
Shared: FPS · Multiplayer · Sci-fi

Halo: The Master Chief Collection
Shared: FPS · Co-op · Sci-fi

Titanfall® 2
Shared: FPS · Action · Multiplayer

Call of Duty®: Black Ops II
Shared: FPS · Action · Co-op

Apex Legends™
Shared: FPS · Multiplayer · Action

How to Fish
Shared: Co-op · Online Co-Op · Multiplayer

Orcs Must Die! 2
Shared: Tower Defense · Co-op · Strategy

Borderlands 2
Shared: Co-op · Action · FPS

ORION: Prelude
Shared: FPS · Action · Co-op

Battlefield™ 2042
Shared: FPS · Multiplayer · Action

Insurgency
Shared: FPS · Action · Co-op

Left 4 Dead
Shared: Co-op · FPS · Action

Aliens: Colonial Marines Collection
Shared: FPS · Action · Co-op