Games like Ruin Adventurer
Games like Ruin Adventurer include Factorio, Graveyard Keeper, Totally Accurate Battle Simulator, shapez 2 - Factory, and Automation - The Car Company Tycoon Game. We matched them by the tags players give Ruin Adventurer on Steam (Simulation, Strategy, Sandbox, Exploration, and 2.5D): closest matches first, and among equally close ones the better-known games.

Factorio
Shared: Sandbox · Strategy · Automation

Graveyard Keeper
Shared: Simulation · Pixel Graphics · Sandbox

Totally Accurate Battle Simulator
Shared: Simulation · Sandbox · Strategy

shapez 2 - Factory
Shared: Strategy · Simulation · Automation

Automation - The Car Company Tycoon Game
Shared: Simulation · Sandbox · Strategy

Terraria
Shared: Sandbox · Pixel Graphics · Exploration

Stellaris
Shared: Strategy · Simulation · Exploration

Satisfactory
Shared: Automation · Sandbox · Exploration

Cities: Skylines
Shared: Simulation · Strategy · Sandbox

RimWorld
Shared: Strategy · Sandbox · Simulation

Core Keeper
Shared: Exploration · Sandbox · Pixel Graphics

WorldBox - God Simulator
Shared: Simulation · Sandbox · Pixel Graphics

The Escapists
Shared: Strategy · Simulation · Pixel Graphics

Dwarf Fortress
Shared: Simulation · Strategy · Sandbox

The Last Caretaker
Shared: Sandbox · Automation · Crafting

shapez
Shared: Sandbox · Strategy · Automation

Sandustry
Shared: Sandbox · Automation · Exploration

Stardew Valley
Shared: Simulation · Pixel Graphics · Sandbox

鬼谷八荒 Tale of Immortal
Shared: Simulation · Sandbox · Management

Kenshi
Shared: Sandbox · Simulation · Strategy

Techtonica
Shared: Simulation · Exploration · Automation

Manor Lords
Shared: Strategy · Simulation · Sandbox

Mini Motorways
Shared: Simulation · Strategy · Minimalist

Prison Architect
Shared: Simulation · Sandbox · Strategy