Games like Room Escape: Open Doors
Games like Room Escape: Open Doors include There Is No Game: Wrong Dimension, The Room, Hidden Folks, Morphopolis, and Gorogoa. We matched them by the tags players give Room Escape: Open Doors on Steam (Casual, Adventure, Puzzle, Hidden Object, and 2D): closest matches first, and among equally close ones the better-known games.

There Is No Game: Wrong Dimension
Shared: Puzzle · Adventure · Indie

The Room
Shared: Puzzle · Adventure · Singleplayer

Hidden Folks
Shared: Casual · Hidden Object · Puzzle

Morphopolis
Shared: Puzzle · Casual · Hidden Object

Gorogoa
Shared: Puzzle · Casual · Indie

Strange Jigsaws
Shared: Casual · Adventure · Puzzle

Zup! S
Shared: Casual · Puzzle · 2D

Pikuniku
Shared: Adventure · Casual · Puzzle

Scribblenauts Unlimited
Shared: Casual · Puzzle · Adventure

LIMBO
Shared: Puzzle · Indie · Adventure

Varenje
Shared: Adventure · Casual · Puzzle

BEEP
Shared: Adventure · Indie · 2D

My Brother Rabbit
Shared: Adventure · Puzzle · Singleplayer

FEZ
Shared: Puzzle · Indie · Adventure

The Room Two
Shared: Puzzle · Hidden Object · Adventure

Zup! 2
Shared: Casual · Puzzle · 2D

Moncage
Shared: Casual · Puzzle · Adventure

The Room Three
Shared: Puzzle · Adventure · Indie

Little Inferno
Shared: Casual · Puzzle · Indie

Melvor Idle
Shared: Casual · Adventure · Singleplayer

Frankenstein: Master of Death
Shared: Casual · Hidden Object · Puzzle

Nihilumbra
Shared: Adventure · Casual · Puzzle

Donut County
Shared: Casual · Puzzle · Indie

Chants of Sennaar
Shared: Adventure · Puzzle · Singleplayer