Games like Role of Hex
Games like Role of Hex include FTL: Faster Than Light, Dungeon of the ENDLESS™, No Man's Sky, Tower Dominion, and Dune: Awakening. We matched them by the tags players give Role of Hex on Steam (Roguelike, Tower Defense, Procedural Generation, Exploration, and PvE): closest matches first, and among equally close ones the better-known games.

FTL: Faster Than Light
Shared: Roguelike · Sci-fi · Procedural Generation

Dungeon of the ENDLESS™
Shared: Roguelike · Tower Defense · Sci-fi

No Man's Sky
Shared: Exploration · Open World Survival Craft · Sci-fi

Tower Dominion
Shared: Tower Defense · Roguelike · Procedural Generation

Dune: Awakening
Shared: Exploration · Open World Survival Craft · PvE

The King is Watching
Shared: Roguelike · Tower Defense · Base Building

Wall World
Shared: Tower Defense · Roguelike · Exploration

The Binding of Isaac
Shared: Roguelike · Procedural Generation · Action Roguelike

Don't Starve
Shared: Open World Survival Craft · Roguelike · Exploration

Dome Keeper
Shared: Roguelike · Tower Defense · Sci-fi

Stoneshard
Shared: Roguelike · Procedural Generation · Open World Survival Craft

Mindustry
Shared: Tower Defense · Base Building · Strategy

Rogue Tower
Shared: Tower Defense · Roguelike · Procedural Generation

Deep Rock Galactic
Shared: Procedural Generation · PvE · Exploration

Kingdom: New Lands
Shared: Tower Defense · Roguelike · Exploration

Heat Signature
Shared: Roguelike · Procedural Generation · Sci-fi

Subnautica
Shared: Open World Survival Craft · Exploration · Base Building

Axon TD: Uprising - Tower Defense
Shared: Tower Defense · Roguelike · PvE

Nordhold
Shared: Tower Defense · Roguelike · Strategy

Lethal Company
Shared: Exploration · Sci-fi · PvE

Tower Factory
Shared: Tower Defense · Roguelike · Procedural Generation

Nordic Ashes: Survivors of Ragnarok
Shared: Exploration · Roguelike · Procedural Generation

Drill Core
Shared: Tower Defense · Roguelike · Exploration

Creeper World 3: Arc Eternal
Shared: Tower Defense · Sci-fi · Strategy