Games like Return to Mysterious Island
Games like Return to Mysterious Island include The Room 4: Old Sins, The Room, Monument Valley, Slime Rancher, and Syberia. We matched them by the tags players give Return to Mysterious Island on Steam (Adventure, Point & Click, Casual, Puzzle, and Female Protagonist): closest matches first, and among equally close ones the better-known games.

The Room 4: Old Sins
Shared: Point & Click · Adventure · Puzzle

The Room
Shared: Point & Click · Puzzle · Adventure

Monument Valley
Shared: Adventure · Puzzle · Casual

Slime Rancher
Shared: Adventure · Exploration · First-Person

Syberia
Shared: Adventure · Point & Click · Puzzle

Portal 2
Shared: Puzzle · Singleplayer · First-Person

Rise of the Tomb Raider™
Shared: Adventure · Female Protagonist · Singleplayer

Tomb Raider Game of the Year
Shared: Adventure · Female Protagonist · Singleplayer

Escape Simulator
Shared: Puzzle · Adventure · First-Person

Chants of Sennaar
Shared: Adventure · Puzzle · Point & Click

Call of the Sea
Shared: Adventure · Puzzle · First-Person

There Is No Game: Wrong Dimension
Shared: Point & Click · Adventure · Puzzle

The Room Three
Shared: Adventure · Puzzle · Point & Click

The Room Two
Shared: Point & Click · Puzzle · Adventure

Big Walk
Shared: Puzzle · Adventure · Exploration

Myst
Shared: Adventure · Puzzle · First-Person

The Witness
Shared: Puzzle · First-Person · Exploration

Syberia: The World Before
Shared: Adventure · Point & Click · Puzzle

Iris.Fall
Shared: Adventure · Casual · Puzzle

Silence
Shared: Adventure · Point & Click · Puzzle

Broken Age
Shared: Adventure · Point & Click · Puzzle

Gorogoa
Shared: Puzzle · Casual · Point & Click

Riven (1997)
Shared: Adventure · Point & Click · Puzzle

Boxes: Lost Fragments
Shared: Point & Click · Adventure · Puzzle