Games like Quadrix
Games like Quadrix include Slay the Spire 2, Inscryption, Slay the Spire, Balatro, and 9 Kings. We matched them by the tags players give Quadrix on Steam (Puzzle, Falling Blocks, Roguelite, Card Battler, and Score Attack): closest matches first, and among equally close ones the better-known games.

Slay the Spire 2
Shared: Card Game · Roguelike · Strategy

Inscryption
Shared: Card Battler · Card Game · Puzzle

Slay the Spire
Shared: Card Battler · Card Game · Roguelike

Balatro
Shared: Card Game · Roguelike · Roguelite

9 Kings
Shared: Strategy · Card Game · Roguelike

Monster Train
Shared: Roguelite · Card Battler · Card Game

Drop Duchy
Shared: Falling Blocks · Roguelite · Card Battler

Dicey Dungeons
Shared: Card Battler · Roguelite · Roguelike

Loop Hero
Shared: Roguelite · Roguelike · Tactical

Across the Obelisk
Shared: Card Game · Tactical · Card Battler

Stacklands
Shared: Roguelite · Card Game · Card Battler

DICEOMANCER
Shared: Card Battler · Card Game · Strategy

Vampire Crawlers: The Turbo Wildcard from Vampire Survivors
Shared: Card Battler · Roguelike · Card Game

Griftlands
Shared: Roguelite · Card Battler · Card Game

Dungeons & Degenerate Gamblers
Shared: Roguelike · Card Battler · Card Game

The Legend of Bum-Bo
Shared: Roguelite · Puzzle · Strategy

Ratropolis
Shared: Roguelite · Card Battler · Card Game

Into the Breach
Shared: Puzzle · Strategy · Roguelite

Tetris® Effect: Connected
Shared: Puzzle · Falling Blocks · Multiplayer

Vampire Survivors
Shared: Roguelite · Roguelike · Indie

Wildfrost
Shared: Card Battler · Roguelite · Card Game

Die in the Dungeon
Shared: Roguelike · Card Game · Strategy

Emberward
Shared: Falling Blocks · Roguelite · Strategy

Super Fantasy Kingdom
Shared: Roguelite · Strategy · Roguelike