Games like Pyxel Knight
Games like Pyxel Knight include Celeste, Super Meat Boy, Hollow Knight, Broforce, and SANABI. We matched them by the tags players give Pyxel Knight on Steam (Metroidvania, Precision Platformer, 2D Platformer, Platformer, and 2D): closest matches first, and among equally close ones the better-known games.

Celeste
Shared: Precision Platformer · Platformer · 2D Platformer

Super Meat Boy
Shared: Precision Platformer · Platformer · 2D Platformer

Hollow Knight
Shared: Metroidvania · Platformer · 2D

Broforce
Shared: Action · 2D · Platformer

SANABI
Shared: 2D Platformer · Action · Pixel Graphics

VVVVVV
Shared: Precision Platformer · Platformer · 2D Platformer

Dead Cells
Shared: Metroidvania · 2D · Adventure

Dust: An Elysian Tail
Shared: Metroidvania · Platformer · Action

Skul: The Hero Slayer
Shared: Action · 2D · Metroidvania

Hollow Knight: Silksong
Shared: Metroidvania · 2D · Platformer

The Messenger
Shared: Metroidvania · Platformer · 2D

Owlboy
Shared: Metroidvania · Platformer · 2D

Blasphemous
Shared: Metroidvania · 2D · Pixel Graphics

Ori and the Will of the Wisps
Shared: Metroidvania · Platformer · Action

Blasphemous 2
Shared: Metroidvania · 2D Platformer · Fantasy

BattleBlock Theater®
Shared: Platformer · 2D · 2D Platformer

Rusted Moss
Shared: Metroidvania · Platformer · Action

Bread & Fred
Shared: 2D Platformer · Precision Platformer · Platformer

Katana ZERO
Shared: Action · Platformer · 2D Platformer

Downwell
Shared: Precision Platformer · Platformer · 2D Platformer

Momodora: Reverie Under The Moonlight
Shared: Metroidvania · 2D Platformer · 2D

UnEpic
Shared: Metroidvania · Platformer · Action

Leap Year
Shared: Precision Platformer · 2D Platformer · Metroidvania

Nine Sols
Shared: Metroidvania · Platformer · 2D