Games like Professor Lupo: Ocean
Games like Professor Lupo: Ocean include Deponia, Gorogoa, There Is No Game: Wrong Dimension, Sally Face - Episode One, and GRIS. We matched them by the tags players give Professor Lupo: Ocean on Steam (Adventure, Indie, Point & Click, Hand-drawn, and Puzzle): closest matches first, and among equally close ones the better-known games.

Deponia
Shared: Adventure · Point & Click · Puzzle

Gorogoa
Shared: Indie · Hand-drawn · Puzzle

There Is No Game: Wrong Dimension
Shared: Indie · Adventure · Point & Click

Sally Face - Episode One
Shared: Indie · Adventure · Puzzle

GRIS
Shared: Indie · Adventure · Hand-drawn

Machinarium
Shared: Point & Click · Hand-drawn · Puzzle

Rusty Lake Paradise
Shared: Indie · Point & Click · Adventure

Chants of Sennaar
Shared: Adventure · Indie · Puzzle

Servant of the Lake
Shared: Adventure · Point & Click · Puzzle

Fran Bow
Shared: Point & Click · Adventure · Puzzle

The White Door
Shared: Adventure · Indie · Point & Click

Samsara Room
Shared: Indie · Adventure · Puzzle

Papers, Please
Shared: Indie · Point & Click · Puzzle

Chaos on Deponia
Shared: Adventure · Point & Click · Indie

Broken Age
Shared: Adventure · Point & Click · Indie

The Dark Eye: Chains of Satinav
Shared: Adventure · Point & Click · Indie

Deponia Doomsday
Shared: Adventure · Point & Click · Indie

Deponia: The Complete Journey
Shared: Adventure · Point & Click · Puzzle

Return to Monkey Island
Shared: Adventure · Point & Click · Puzzle

Hollow Knight
Shared: Indie · 2D · Adventure

Hollow Knight: Silksong
Shared: Indie · 2D · Adventure

Outer Wilds
Shared: Adventure · Puzzle · Indie

OneShot
Shared: Indie · Puzzle · Adventure

The Whispered World: Special Edition
Shared: Adventure · Indie · Point & Click