Games like Prison Life 2
Games like Prison Life 2 include Town of Salem, Who's Your Daddy?!, Stardew Valley, Liars Bar, and Plague Inc: Evolved. We matched them by the tags players give Prison Life 2 on Steam (RPG, Detective, Strategy, Casual, and Simulation): closest matches first, and among equally close ones the better-known games.

Town of Salem
Shared: Strategy · RPG · Multiplayer

Who's Your Daddy?!
Shared: Multiplayer · Simulation · Strategy

Stardew Valley
Shared: RPG · Multiplayer · Simulation

Liars Bar
Shared: Casual · Multiplayer · Indie

Plague Inc: Evolved
Shared: Strategy · Simulation · Indie

Dale & Dawson Stationery Supplies
Shared: Casual · RPG · Multiplayer

Mount & Blade II: Bannerlord
Shared: Strategy · RPG · Multiplayer

Bloons TD 6
Shared: Strategy · Multiplayer · Casual

Feign
Shared: RPG · Multiplayer · Social Deduction

Don't Starve Together
Shared: Multiplayer · Co-op · RPG

Golf With Your Friends
Shared: Casual · Multiplayer · Indie

Garry's Mod
Shared: Multiplayer · Casual · Simulation

Overcooked! 2
Shared: Multiplayer · Casual · Co-op

The Escapists 2
Shared: Strategy · Multiplayer · Simulation

PowerWash Simulator
Shared: Casual · Simulation · Multiplayer

For The King
Shared: RPG · Strategy · Multiplayer

Heroes of Might and Magic: Olden Era
Shared: RPG · Strategy · Simulation

Phasmophobia
Shared: Multiplayer · Co-op · Detective

The Scroll of Taiwu : Beyond The Dome
Shared: RPG · Strategy · Indie

Among Us
Shared: Multiplayer · Social Deduction · Online Co-Op

Schedule I
Shared: Simulation · Multiplayer · Co-op

Chinese Parents
Shared: RPG · Casual · Simulation

Plebby Quest: The Crusades
Shared: Strategy · RPG · Casual

Farm Together
Shared: Simulation · Multiplayer · Casual