Games like Potio Mellow
Games like Potio Mellow include Terraria, DAVE THE DIVER, Stoneshard, Dead Cells, and Graveyard Keeper. We matched them by the tags players give Potio Mellow on Steam (Strategy, Adventure, Roguelike, Sandbox, and 2D): closest matches first, and among equally close ones the better-known games.

Terraria
Shared: Sandbox · Adventure · 2D

DAVE THE DIVER
Shared: Adventure · Pixel Graphics · Management

Stoneshard
Shared: Roguelike · Strategy · Pixel Graphics

Dead Cells
Shared: Adventure · Roguelike · 2D

Graveyard Keeper
Shared: Pixel Graphics · Sandbox · Management

The Escapists
Shared: Strategy · Pixel Graphics · 2D

Noita
Shared: Roguelike · Pixel Graphics · Sandbox

Balatro
Shared: Roguelike · Strategy · Pixel Graphics

Stardew Valley
Shared: Pixel Graphics · Sandbox · Relaxing

Planet Coaster
Shared: Sandbox · Strategy · Management

Starbound
Shared: Sandbox · Adventure · Pixel Graphics

Forager
Shared: Pixel Graphics · Sandbox · Adventure

Factorio
Shared: Strategy · Sandbox · Management

Don't Starve
Shared: Adventure · Sandbox · Roguelike

Game Dev Tycoon
Shared: Strategy · Management · 2D

RimWorld
Shared: Strategy · Sandbox · Management

The Escapists 2
Shared: Strategy · Pixel Graphics · 2D

The Scroll of Taiwu : Beyond The Dome
Shared: Sandbox · Strategy · Adventure

Totally Accurate Battle Simulator
Shared: Sandbox · Strategy · Adventure

鬼谷八荒 Tale of Immortal
Shared: Sandbox · Management · Adventure

Potion Craft: Alchemist Simulator
Shared: Relaxing · 2D · Management

Skul: The Hero Slayer
Shared: Roguelike · Pixel Graphics · 2D

Swag and Sorcery
Shared: Pixel Graphics · Adventure · Management

The Binding of Isaac: Rebirth
Shared: Roguelike · Pixel Graphics · 2D