Games like Pixel City
Games like Pixel City include Stardew Valley, Terraria, Paralives, Kenshi, and Big Ambitions. We matched them by the tags players give Pixel City on Steam (Simulation, Life Sim, 2D, Open World, and Sandbox): closest matches first, and among equally close ones the better-known games.

Stardew Valley
Shared: Life Sim · Pixel Graphics · Simulation

Terraria
Shared: Sandbox · 2D · Survival

Paralives
Shared: Life Sim · Simulation · Open World

Kenshi
Shared: Open World · Sandbox · Simulation

Big Ambitions
Shared: Simulation · Life Sim · Sandbox

Noita
Shared: Pixel Graphics · Sandbox · 2D

Oxygen Not Included
Shared: 2D · Survival · Simulation

Core Keeper
Shared: Open World · Pixel Graphics · Survival

Don't Starve
Shared: Survival · Sandbox · Open World

Don't Starve Together
Shared: Open World · Survival · Sandbox

Project Zomboid
Shared: Open World · Survival · Sandbox

The Sims™ 4
Shared: Life Sim · Simulation · Sandbox

Forager
Shared: Pixel Graphics · 2D · Survival

Space Engineers
Shared: Simulation · Sandbox · Open World

My Time at Portia
Shared: Life Sim · Open World · Simulation

inZOI
Shared: Life Sim · Simulation · Sandbox

People Playground
Shared: Sandbox · 2D · Simulation

The Long Dark
Shared: Open World · Survival · Simulation

The Guild 3
Shared: Life Sim · Simulation · Economy

Elin
Shared: Open World · Pixel Graphics · Sandbox

Supermarket Simulator
Shared: Simulation · Life Sim · Economy

WorldBox - God Simulator
Shared: Simulation · Sandbox · Life Sim

RimWorld
Shared: Sandbox · Simulation · Survival

My Summer Car
Shared: Simulation · Open World · Survival