Games like Picaro
Games like Picaro include Slay the Spire 2, Slay the Spire, Balatro, Vampire Crawlers: The Turbo Wildcard from Vampire Survivors, and Darkest Dungeon®. We matched them by the tags players give Picaro on Steam (Strategy, Card Game, Card Battler, Roguelike, and Turn-Based Combat): closest matches first, and among equally close ones the better-known games.

Slay the Spire 2
Shared: Card Game · Roguelike · Strategy

Slay the Spire
Shared: Card Game · Card Battler · Roguelike

Balatro
Shared: Card Game · Roguelike · Strategy

Vampire Crawlers: The Turbo Wildcard from Vampire Survivors
Shared: Card Battler · Strategy · Roguelike

Darkest Dungeon®
Shared: Turn-Based Combat · Roguelike · Dungeon Crawler

Die in the Dungeon
Shared: Strategy · Roguelike · Card Game

9 Kings
Shared: Strategy · Card Game · Roguelike

Inscryption
Shared: Card Game · Card Battler · Roguelike

Dice & Fold
Shared: Card Battler · Roguelike · Turn-Based Combat

Griftlands
Shared: Card Battler · Card Game · Strategy

Library Of Ruina
Shared: Card Game · Strategy · Turn-Based Combat

DICEOMANCER
Shared: Strategy · Card Game · Card Battler

Breachway
Shared: Strategy · Card Game · Roguelike

The Binding of Isaac: Rebirth
Shared: Roguelike · Indie · Dungeon Crawler

Super Fantasy Kingdom
Shared: Strategy · Roguelike · Card Game

Monster Train
Shared: Card Battler · Card Game · Roguelike

Dicey Dungeons
Shared: Card Battler · Roguelike · Strategy

Stacklands
Shared: Card Game · Card Battler · Strategy

Dungeons & Degenerate Gamblers
Shared: Strategy · Card Game · Roguelike

Roguebook
Shared: Card Game · Strategy · Indie

He is Coming
Shared: Strategy · Roguelike · Card Game

Nubby's Number Factory
Shared: Strategy · Roguelike · Indie

Vault of the Void
Shared: Strategy · Indie · Card Battler

Astrea: Six-Sided Oracles
Shared: Card Battler · Card Game · Strategy