Games like Persephone
Games like Persephone include Hollow Knight: Silksong, Baba Is You, Carto, GRIS, and Celeste. We matched them by the tags players give Persephone on Steam (Indie, Puzzle, Female Protagonist, Isometric, and Cute): closest matches first, and among equally close ones the better-known games.

Hollow Knight: Silksong
Shared: Indie · Singleplayer · 2D

Baba Is You
Shared: Indie · Puzzle · Singleplayer

Carto
Shared: Indie · Puzzle · Cute

GRIS
Shared: Indie · Female Protagonist · Singleplayer

Celeste
Shared: Indie · Female Protagonist · Difficult

Unpacking
Shared: Cute · Puzzle · Indie

Assemble with Care
Shared: Indie · Puzzle · Female Protagonist

Portal 2
Shared: Puzzle · Singleplayer · Female Protagonist

Zup! S
Shared: Puzzle · Indie · 2D

Muse Dash
Shared: Cute · Female Protagonist · Singleplayer

OneShot
Shared: Indie · Puzzle · Cute

The Last Campfire
Shared: Puzzle · Indie · Cute

Timelie
Shared: Puzzle · Female Protagonist · Isometric

ENDER LILIES: Quietus of the Knights
Shared: Female Protagonist · Singleplayer · Indie

Changed
Shared: Cute · Puzzle · Indie

Chants of Sennaar
Shared: Puzzle · Indie · Singleplayer

Cat Goes Fishing
Shared: Indie · Cute · 2D

Hollow Knight
Shared: Indie · 2D · Singleplayer

World of Goo
Shared: Indie · Puzzle · Singleplayer

LIMBO
Shared: Indie · Puzzle · 2D

When The Past Was Around
Shared: Female Protagonist · Cute · Puzzle

LEGO® Builder's Journey
Shared: Indie · Cute · Puzzle

Is This Seat Taken?
Shared: Puzzle · Cute · Singleplayer

Slime Rancher 2
Shared: Cute · Singleplayer · Relaxing