Games like Panic Poopers
Games like Panic Poopers include Vampire Survivors, The Binding of Isaac, BALL x PIT, Spelunky, and Rogue Legacy 2. We matched them by the tags players give Panic Poopers on Steam (PvE, Arcade, Roguelike, 2D, and Top-Down): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: 2D · Roguelike · Arcade

The Binding of Isaac
Shared: Roguelike · Procedural Generation · Top-Down

BALL x PIT
Shared: Arcade · Roguelike · Action

Spelunky
Shared: Roguelike · 2D · Arcade

Rogue Legacy 2
Shared: Arcade · Action · 2D

Shower With Your Dad Simulator 2015: Do You Still Shower With Your Dad
Shared: Arcade · 2D · Funny

Skul: The Hero Slayer
Shared: Roguelike · 2D · Action

Timberman
Shared: 2D · Arcade · Action

Rogue Legacy
Shared: Roguelike · 2D · Action

The Binding of Isaac: Rebirth
Shared: Roguelike · Indie · 2D

Have a Nice Death
Shared: 2D · Funny · Roguelike

Nubby's Number Factory
Shared: Roguelike · Arcade · 2D

Heat Signature
Shared: Roguelike · Top-Down · Action

Risk of Rain Returns
Shared: PvE · 2D · Roguelike

Rogue: Genesia
Shared: Arcade · PvE · Roguelike

FTL: Faster Than Light
Shared: Roguelike · Singleplayer · Indie

Megabonk
Shared: Roguelike · Arcade · Indie

Dead Cells
Shared: Roguelike · 2D · Action

Deep Rock Galactic: Survivor
Shared: PvE · Top-Down · Arcade

A Dance of Fire and Ice
Shared: Arcade · 2D · Singleplayer

SUPER CHICKEN JUMPER
Shared: Arcade · 2D · Funny

To The Core
Shared: Arcade · 2D · Procedural Generation

Kingdom Rush - Tower Defense
Shared: 2D · Singleplayer · Funny

DR LIVESEY ROM AND DEATH EDITION
Shared: Roguelike · Action · Cartoon