Games like Osiris
Games like Osiris include Hades, Hades II, Wolcen: Lords of Mayhem, Last Epoch, and Hero Siege. We matched them by the tags players give Osiris on Steam (Action Roguelike, Hack and Slash, Perma Death, Action RPG, and RPG): closest matches first, and among equally close ones the better-known games.

Hades
Shared: Action Roguelike · Hack and Slash · Roguelike

Hades II
Shared: Hack and Slash · Action Roguelike · Roguelike

Wolcen: Lords of Mayhem
Shared: Hack and Slash · Action RPG · RPG

Last Epoch
Shared: Hack and Slash · Action RPG · RPG

Hero Siege
Shared: Hack and Slash · Action Roguelike · Action RPG

Grim Dawn
Shared: Hack and Slash · Action RPG · RPG

Path of Exile 2
Shared: Hack and Slash · Action RPG · RPG

Black Myth: Wukong
Shared: Action RPG · RPG · Action

Halls of Torment
Shared: Action Roguelike · Action RPG · Roguelike

Diablo® IV
Shared: Hack and Slash · Action RPG · RPG

Path of Exile
Shared: Hack and Slash · Action RPG · RPG

Heroes of Hammerwatch II
Shared: Action Roguelike · RPG · Action RPG

Death Must Die
Shared: Action Roguelike · Hack and Slash · RPG

Soulstone Survivors
Shared: Action Roguelike · Action RPG · Hack and Slash

Jotunnslayer: Hordes of Hel
Shared: Action Roguelike · Hack and Slash · Action RPG

Warhammer 40,000: Inquisitor - Martyr
Shared: Hack and Slash · Action RPG · RPG

Moonlighter
Shared: Hack and Slash · Action Roguelike · Roguelike

Cinderia
Shared: Action Roguelike · Hack and Slash · Roguelike

No Rest for the Wicked
Shared: Hack and Slash · Action RPG · RPG

Children of Morta
Shared: Hack and Slash · Action Roguelike · Roguelike

暖雪 Warm Snow
Shared: Action Roguelike · Roguelike · RPG

Titan Quest II
Shared: Hack and Slash · Action RPG · RPG

Torchlight II
Shared: Hack and Slash · Action RPG · RPG

VOIN
Shared: Hack and Slash · Action Roguelike · RPG