Games like Orpheus's Dream
Games like Orpheus's Dream include Samsara Room, Varenje, There Is No Game: Wrong Dimension, Pikuniku, and Poppy Playtime. We matched them by the tags players give Orpheus's Dream on Steam (Free to Play, Adventure, Indie, Casual, and Puzzle): closest matches first, and among equally close ones the better-known games.

Samsara Room
Shared: Indie · Adventure · Free to Play

Varenje
Shared: Free to Play · Adventure · Indie

There Is No Game: Wrong Dimension
Shared: Indie · Adventure · Puzzle

Pikuniku
Shared: Adventure · Indie · Casual

Poppy Playtime
Shared: Free to Play · Puzzle · Indie

Idle Champions of the Forgotten Realms
Shared: Free to Play · Adventure · Indie

We Were Here
Shared: Free to Play · Puzzle · Adventure

The Mr. Rabbit Magic Show
Shared: Adventure · Free to Play · Puzzle

Where Winds Meet
Shared: Free to Play · Adventure · Indie

Donut County
Shared: Indie · Casual · Puzzle

Tick Tock: A Tale for Two
Shared: Adventure · Puzzle · Indie

Moncage
Shared: Indie · Casual · Puzzle

Gorogoa
Shared: Indie · Puzzle · Casual

The Room
Shared: Puzzle · Adventure · Indie

Little Inferno
Shared: Indie · Casual · Puzzle

Morphopolis
Shared: Indie · Puzzle · Adventure

Chants of Sennaar
Shared: Adventure · Puzzle · Indie

Iris.Fall
Shared: Adventure · Indie · Casual

FEZ
Shared: Indie · Puzzle · Adventure

Strange Jigsaws
Shared: Adventure · Casual · Puzzle

Palia
Shared: Free to Play · Casual · Adventure

Human Fall Flat
Shared: Puzzle · Adventure · Indie

Travellin Cats in Paris
Shared: Free to Play · Puzzle · Casual

Outcore: Desktop Adventure
Shared: Adventure · Free to Play · Puzzle