Games like Orpheus' Revenge
Games like Orpheus' Revenge include Vampire Survivors, Timberman, Broforce, Exit the Gungeon, and Hotline Miami. We matched them by the tags players give Orpheus' Revenge on Steam (Action, Arcade, Incremental, Singleplayer, and Pixel Graphics): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: Pixel Graphics · Singleplayer · 2D

Timberman
Shared: Action · Pixel Graphics · Arcade

Broforce
Shared: Action · Pixel Graphics · 2D

Exit the Gungeon
Shared: Arcade · Action · Pixel Graphics

Hotline Miami
Shared: Action · Pixel Graphics · Indie

Skul: The Hero Slayer
Shared: Action · Pixel Graphics · Singleplayer

LUFTRAUSERS
Shared: Arcade · Action · Pixel Graphics

Hotline Miami 2: Wrong Number
Shared: Action · Pixel Graphics · Singleplayer

A Dance of Fire and Ice
Shared: Singleplayer · Arcade · 2D

Shelldiver
Shared: Incremental · Arcade · 2D

UFO 50
Shared: Action · Pixel Graphics · Arcade

SANABI
Shared: Action · Pixel Graphics · Singleplayer

Five Nights at Freddy's: Into the Pit
Shared: Pixel Graphics · Singleplayer · 2D

Planes, Bullets and Vodka
Shared: Action · Arcade · Shooter

Kung Fury: Street Rage - Ultimate Edition
Shared: Arcade · Action · Pixel Graphics

Papers, Please
Shared: Singleplayer · Pixel Graphics · Point & Click

Blasphemous
Shared: Pixel Graphics · Action · 2D

Halls of Torment
Shared: Pixel Graphics · Action · Arcade

Rhythm Doctor
Shared: Pixel Graphics · Action · Singleplayer

Warhammer 40,000: Boltgun
Shared: Action · Pixel Graphics · Shooter

Huntdown
Shared: Action · Pixel Graphics · Shooter

SUPER CHICKEN JUMPER
Shared: Arcade · Pixel Graphics · 2D

Katana ZERO
Shared: Action · Pixel Graphics · 2D

BALL x PIT
Shared: Action · Arcade · Pixel Graphics