Games like Orion Sandbox Enhanced
Games like Orion Sandbox Enhanced include Terraria, Don't Starve Together, Rust, Starbound, and Portal Knights. We matched them by the tags players give Orion Sandbox Enhanced on Steam (Action, Adventure, Casual, Indie, and RPG): closest matches first, and among equally close ones the better-known games.

Terraria
Shared: Sandbox · Adventure · Survival

Don't Starve Together
Shared: Adventure · Survival · Multiplayer

Rust
Shared: Survival · Adventure · Multiplayer

Starbound
Shared: Adventure · Sandbox · Survival

Portal Knights
Shared: Adventure · RPG · Sandbox

Last Oasis
Shared: Action · Adventure · RPG

Wobbly Life
Shared: Adventure · Sandbox · Action

Forager
Shared: Indie · Survival · Adventure

ARK: Survival Ascended
Shared: Survival · Adventure · Action

Palworld
Shared: Survival · Indie · Adventure

PixARK
Shared: Adventure · Survival · Action

Necesse
Shared: Adventure · Sandbox · Multiplayer

Pikuniku
Shared: Adventure · Indie · Casual

ARK: Survival Evolved
Shared: Adventure · Survival · Multiplayer

Mount & Blade II: Bannerlord
Shared: RPG · Action · Sandbox

Don't Starve
Shared: Adventure · Indie · Survival

Mount & Blade: Warband
Shared: RPG · Action · Sandbox

Keplerth
Shared: Adventure · Sandbox · Casual

Cat Quest
Shared: Adventure · Action · RPG

Once Human
Shared: Action · Survival · Multiplayer

Human Fall Flat
Shared: Adventure · Action · Sandbox

Stardew Valley
Shared: RPG · Multiplayer · Sandbox

Monster Hunter: World
Shared: Action · RPG · Adventure

Town of Salem
Shared: Indie · Casual · RPG