Games like Open Fire
Games like Open Fire include Vampire Survivors, Balatro, Vampire Crawlers: The Turbo Wildcard from Vampire Survivors, Death Must Die, and Slay the Spire. We matched them by the tags players give Open Fire on Steam (Action, Casual, RPG, Strategy, and Action Roguelike): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: Action Roguelike · Casual · Action

Balatro
Shared: Card Game · Roguelike · Strategy

Vampire Crawlers: The Turbo Wildcard from Vampire Survivors
Shared: Strategy · Action · Card Battler

Death Must Die
Shared: Action Roguelike · RPG · Action

Slay the Spire
Shared: Card Game · Strategy · Roguelike

Slay the Spire 2
Shared: Card Game · Roguelike · Strategy

Skul: The Hero Slayer
Shared: Action · Action Roguelike · Roguelike

UFO 50
Shared: Action · Strategy · RPG

9 Kings
Shared: RPG · Strategy · Card Game

Overdungeon
Shared: Strategy · RPG · Casual

Rogue Legacy
Shared: Action · Action Roguelike · Roguelike

Streets of Rogue
Shared: Action Roguelike · RPG · Action

Hero Siege
Shared: RPG · Action Roguelike · Action

One Step From Eden
Shared: Action Roguelike · Action · Strategy

Juicy Realm
Shared: Action · RPG · Casual

Hades II
Shared: Action · Roguelike · Action Roguelike

Hades
Shared: Action Roguelike · Action · Roguelike

Dead Cells
Shared: Action Roguelike · Roguelike · Action

Dungreed
Shared: Action · Action Roguelike · Roguelike

Across the Obelisk
Shared: Casual · Card Game · Roguelike

Heroes of Hammerwatch II
Shared: RPG · Action · Action Roguelike

Megabonk
Shared: Action Roguelike · Roguelike · Action

Stoneshard
Shared: RPG · Strategy · Roguelike

Hand of Fate
Shared: RPG · Roguelike · Action