Games like Nuclear Design Bureau
Games like Nuclear Design Bureau include People Playground, Kerbal Space Program, Totally Accurate Battle Simulator, Noita, and Bridge Constructor Portal. We matched them by the tags players give Nuclear Design Bureau on Steam (Simulation, Strategy, Physics, Cold War, and Science): closest matches first, and among equally close ones the better-known games.

People Playground
Shared: Physics · Sandbox · Simulation

Kerbal Space Program
Shared: Simulation · Physics · Sandbox

Totally Accurate Battle Simulator
Shared: Simulation · Strategy · Sandbox

Noita
Shared: Physics · Sandbox · Pixel Graphics

Bridge Constructor Portal
Shared: Simulation · Strategy · Physics

Besiege
Shared: Simulation · Physics · Sandbox

Universe Sandbox
Shared: Simulation · Physics · Sandbox

Crazy Machines 3
Shared: Simulation · Physics · Strategy

The Escapists
Shared: Strategy · Simulation · Pixel Graphics

BeamNG.drive
Shared: Simulation · Physics · Sandbox

Poly Bridge 2
Shared: Physics · Simulation · Puzzle

Poly Bridge
Shared: Simulation · Physics · Puzzle

Hardspace: Shipbreaker
Shared: Simulation · Physics · Sandbox

Teardown
Shared: Physics · Sandbox · Destruction

Papers, Please
Shared: Simulation · Pixel Graphics · Puzzle

WorldBox - God Simulator
Shared: Simulation · Sandbox · Pixel Graphics

Kerbal Space Program 2
Shared: Physics · Sandbox · Simulation

The Escapists 2
Shared: Strategy · Simulation · Pixel Graphics

Reus
Shared: Strategy · Simulation · Sandbox

Game Dev Tycoon
Shared: Simulation · Strategy · 2D

Mini Metro
Shared: Strategy · Simulation · Puzzle

Sand:box
Shared: Simulation · Sandbox · 2D

Spaceflight Simulator
Shared: Simulation · Sandbox · Science

We Who Are About To Die
Shared: Strategy · Simulation · Physics