Games like Nightwire
Games like Nightwire include This War of Mine, Uplink, RimWorld, Cyber Manhunt, and Oxygen Not Included. We matched them by the tags players give Nightwire on Steam (Simulation, Strategy, 2D, Atmospheric, and Cyberpunk): closest matches first, and among equally close ones the better-known games.

This War of Mine
Shared: Atmospheric · Strategy · Simulation

Uplink
Shared: Simulation · Hacking · Strategy

RimWorld
Shared: Strategy · Simulation · Base Building

Cyber Manhunt
Shared: Simulation · Hacking · Mystery

Oxygen Not Included
Shared: 2D · Simulation · Base Building

Hacknet
Shared: Simulation · Hacking · Atmospheric

Dyson Sphere Program
Shared: Simulation · Automation · Base Building

Beholder
Shared: Strategy · Atmospheric · Simulation

Factorio
Shared: Strategy · Automation · Base Building

Prison Architect
Shared: Simulation · Strategy · 2D

Beholder 2
Shared: Strategy · Simulation · Atmospheric

911 Operator
Shared: Simulation · Strategy · 2D

Plague Inc: Evolved
Shared: Simulation · Strategy · Indie

Papers, Please
Shared: Simulation · Atmospheric · 2D

Captain of Industry
Shared: Simulation · Strategy · Automation

Russian Life Simulator
Shared: Simulation · 2D · Strategy

Frostpunk 2
Shared: Strategy · Simulation · Atmospheric

Frostpunk
Shared: Strategy · Simulation · Resource Management

Game Dev Tycoon
Shared: Simulation · Strategy · 2D

shapez
Shared: Strategy · Automation · Base Building

The Red Strings Club
Shared: Cyberpunk · Atmospheric · Choices Matter

Cosmoteer: Starship Architect & Commander
Shared: 2D · Strategy · Sci-fi

Foundation
Shared: Simulation · Strategy · Atmospheric

Mindustry
Shared: Strategy · Automation · Base Building