Games like Mystery Box 2: Evolution
Games like Mystery Box 2: Evolution include The Room, The Room Two, The Room Three, Chants of Sennaar, and The Room 4: Old Sins. We matched them by the tags players give Mystery Box 2: Evolution on Steam (Adventure, Strategy, Point & Click, Puzzle, and Incremental): closest matches first, and among equally close ones the better-known games.

The Room
Shared: Puzzle · Point & Click · Adventure

The Room Two
Shared: Puzzle · Point & Click · Adventure

The Room Three
Shared: Adventure · Puzzle · Point & Click

Chants of Sennaar
Shared: Adventure · Puzzle · Point & Click

The Room 4: Old Sins
Shared: Adventure · Puzzle · Point & Click

The House of Da Vinci
Shared: Puzzle · Point & Click · Hidden Object

Boxes: Lost Fragments
Shared: Adventure · Puzzle · Point & Click

Strange Horticulture
Shared: Puzzle · Point & Click · Adventure

The Eyes of Ara
Shared: Adventure · Puzzle · Point & Click

Rusty Lake Paradise
Shared: Point & Click · Adventure · Puzzle

Blue Prince
Shared: Puzzle · Adventure · First-Person

Servant of the Lake
Shared: Adventure · Puzzle · Point & Click

Morphopolis
Shared: Puzzle · Point & Click · Adventure

Sherlock Holmes: The Devil's Daughter
Shared: Adventure · Puzzle · Detective

The White Door
Shared: Adventure · Point & Click · Puzzle

Sherlock Holmes: Crimes and Punishments
Shared: Adventure · Puzzle · Point & Click

Fran Bow
Shared: Point & Click · Adventure · Puzzle

Machinika Museum
Shared: Puzzle · Point & Click · Adventure

The Roottrees are Dead
Shared: Puzzle · Point & Click · Adventure

The House of Da Vinci 3
Shared: Point & Click · Adventure · Hidden Object

Cyber Manhunt 2: New World - The Hacking Simulator
Shared: Puzzle · Point & Click · Detective

Moncage
Shared: Puzzle · Adventure · Atmospheric

Return of the Obra Dinn
Shared: Puzzle · Adventure · Detective

The House of Tesla: Definitive Edition
Shared: Point & Click · Adventure · Hidden Object