Games like Mutable 50
Games like Mutable 50 include The Binding of Isaac: Rebirth, Skul: The Hero Slayer, Hades, Enter the Gungeon, and Vampire Survivors. We matched them by the tags players give Mutable 50 on Steam (Action, Action Roguelike, Difficult, Stealth, and Pixel Graphics): closest matches first, and among equally close ones the better-known games.

The Binding of Isaac: Rebirth
Shared: Action Roguelike · Difficult · Indie

Skul: The Hero Slayer
Shared: Action · Action Roguelike · Indie

Hades
Shared: Action Roguelike · Action · Indie

Enter the Gungeon
Shared: Action Roguelike · Difficult · Pixel Graphics

Vampire Survivors
Shared: Action Roguelike · Pixel Graphics · Indie

Nuclear Throne
Shared: Action Roguelike · Difficult · Pixel Graphics

Risk of Rain (2013)
Shared: Action Roguelike · Action · Indie

Dungreed
Shared: Action Roguelike · Action · Pixel Graphics

The Binding of Isaac
Shared: Action Roguelike · Difficult · Action

DEADBOLT
Shared: Stealth · Pixel Graphics · Action

Megabonk
Shared: Action Roguelike · Action · Indie

Hotline Miami
Shared: Action · Pixel Graphics · Indie

Celeste
Shared: Difficult · Pixel Graphics · Indie

Noita
Shared: Difficult · Pixel Graphics · Indie

Party Hard
Shared: Stealth · Pixel Graphics · Action

SANABI
Shared: Action · Pixel Graphics · Singleplayer

Hotline Miami 2: Wrong Number
Shared: Action · Pixel Graphics · Difficult

Katana ZERO
Shared: Action · Pixel Graphics · Indie

Rogue Legacy
Shared: Action Roguelike · Action · Indie

Downwell
Shared: Action Roguelike · Pixel Graphics · Action

Wizard of Legend
Shared: Action Roguelike · Pixel Graphics · Action

Gunpoint
Shared: Stealth · Indie · Action

Hyper Light Drifter
Shared: Pixel Graphics · Action · Difficult

Titan Souls
Shared: Difficult · Pixel Graphics · Action