Games like Murder Mystery Machine
Games like Murder Mystery Machine include Chants of Sennaar, Return of the Obra Dinn, L.A. Noire, The White Door, and The Room. We matched them by the tags players give Murder Mystery Machine on Steam (Indie, Adventure, Strategy, Detective, and Isometric): closest matches first, and among equally close ones the better-known games.

Chants of Sennaar
Shared: Adventure · Indie · Puzzle

Return of the Obra Dinn
Shared: Detective · Indie · Puzzle

L.A. Noire
Shared: Detective · Adventure · Crime

The White Door
Shared: Indie · Adventure · Detective

The Room
Shared: Adventure · Puzzle · Indie

Sherlock Holmes: The Devil's Daughter
Shared: Adventure · Detective · Crime

Sherlock Holmes: Crimes and Punishments
Shared: Adventure · Detective · Crime

The Room Three
Shared: Adventure · Indie · Puzzle

Contrast
Shared: Indie · Adventure · Puzzle

This Is the Police
Shared: Strategy · Indie · Crime

Murdered: Soul Suspect
Shared: Adventure · Detective · Mystery

The Rewinder
Shared: Adventure · Detective · Puzzle

The Room Two
Shared: Puzzle · Adventure · Indie

Unheard - Voices of Crime
Shared: Detective · Crime · Indie

Murders on the Yangtze River
Shared: Adventure · Detective · Indie

Disco Elysium - The Final Cut
Shared: Detective · Isometric · Point & Click

Kathy Rain
Shared: Adventure · Indie · Detective

Strange Horticulture
Shared: Detective · Puzzle · Mystery

Phoenix Wright: Ace Attorney Trilogy
Shared: Detective · Adventure · Crime

Rusty Lake Paradise
Shared: Indie · Adventure · Puzzle

The Roottrees are Dead
Shared: Detective · Puzzle · Point & Click

Twelve Minutes
Shared: Indie · Adventure · Puzzle

Tangle Tower
Shared: Detective · Puzzle · Point & Click

1954 Alcatraz
Shared: Adventure · Indie · Point & Click