Games like Mouse Killer
Games like Mouse Killer include Vampire Survivors, Skul: The Hero Slayer, Gunpoint, DELTARUNE, and Hammerfight. We matched them by the tags players give Mouse Killer on Steam (Action, Bullet Hell, 2D, Comedy, and Singleplayer): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: Bullet Hell · 2D · Singleplayer

Skul: The Hero Slayer
Shared: Action · 2D · Indie

Gunpoint
Shared: 2D · Action · Indie

DELTARUNE
Shared: Bullet Hell · Singleplayer · 2D

Hammerfight
Shared: Action · 2D · Mouse Only

LUFTRAUSERS
Shared: Bullet Hell · Action · 2D

Just Shapes & Beats
Shared: Bullet Hell · 2D · Action

Bloody Hell
Shared: Bullet Hell · Singleplayer · Indie

Dungeon Munchies
Shared: Action · Indie · 2D

South Park™: The Stick of Truth™
Shared: Comedy · Action · Singleplayer

Windowkill
Shared: Action · Bullet Hell · 2D

Undertale
Shared: Singleplayer · 2D · Comedy

Exit the Gungeon
Shared: Action · Bullet Hell · 2D

Halo Infinite
Shared: Action · Free to Play · Singleplayer

Rhythm Doctor
Shared: Action · Singleplayer · 2D

Enter the Gungeon
Shared: Bullet Hell · Indie · 2D

My Friend Pedro
Shared: Action · Indie · Singleplayer

Pizza Tower
Shared: Indie · Action · Singleplayer

Broforce
Shared: Action · 2D · Indie

Touhou Koumakyou: New Classic - the Embodiment of Scarlet Devil
Shared: Bullet Hell · Action · 2D

Megabonk
Shared: Bullet Hell · Action · Indie

UnEpic
Shared: Action · Comedy · 2D

One Finger Death Punch
Shared: Action · Singleplayer · Indie

Touhou Fuujinroku ~ Mountain of Faith.
Shared: Action · Bullet Hell · Indie

