Games like Moss Destruction
Games like Moss Destruction include SYNTHETIK: Legion Rising, The Binding of Isaac, Hades, Nuclear Throne, and Skul: The Hero Slayer. We matched them by the tags players give Moss Destruction on Steam (Action, Indie, Roguelite, Twin Stick Shooter, and Procedural Generation): closest matches first, and among equally close ones the better-known games.

SYNTHETIK: Legion Rising
Shared: Indie · Roguelite · Action

The Binding of Isaac
Shared: Indie · Action · Roguelike

Hades
Shared: Roguelite · Indie · Action

Nuclear Throne
Shared: Indie · Action · Roguelike

Skul: The Hero Slayer
Shared: Action · Indie · Roguelite

Hades II
Shared: Action · Roguelite · Roguelike

The Binding of Isaac: Rebirth
Shared: Indie · Roguelike · Difficult

Brigador: Up-Armored Edition
Shared: Action · Twin Stick Shooter · Top-Down Shooter

Enter the Gungeon
Shared: Indie · Roguelike · Difficult

Rogue Legacy 2
Shared: Action · Indie · Roguelite

Megabonk
Shared: Roguelite · Indie · Action

Gunfire Reborn
Shared: Roguelite · Indie · Roguelike

Risk of Rain 2
Shared: Action · Roguelite · Roguelike

RUINER
Shared: Action · Indie · Top-Down Shooter

BALL x PIT
Shared: Action · Roguelite · Roguelike

Ravenswatch
Shared: Action · Roguelike · Roguelite

Risk of Rain (2013)
Shared: Indie · Action · Roguelike

Noita
Shared: Indie · Roguelike · Difficult

Dungreed
Shared: Action · Roguelite · Indie

Teleglitch: Die More Edition
Shared: Indie · Action · Top-Down Shooter

West of Dead
Shared: Roguelite · Roguelike · Action

ScourgeBringer
Shared: Action · Indie · Roguelite

Dandy Ace
Shared: Action · Indie · Roguelite

Star of Providence
Shared: Roguelite · Indie · Action