Games like Molecule - a chemical challenge
Games like Molecule - a chemical challenge include Baba Is You, while True: learn(), SpaceChem, Sokobond, and Stephen's Sausage Roll. We matched them by the tags players give Molecule - a chemical challenge on Steam (Indie, Education, Puzzle, Science, and Difficult): closest matches first, and among equally close ones the better-known games.

Baba Is You
Shared: Indie · Puzzle · Difficult

while True: learn()
Shared: Education · Indie · Puzzle

SpaceChem
Shared: Puzzle · Indie · Difficult

Sokobond
Shared: Science · Puzzle · Sokoban

Stephen's Sausage Roll
Shared: Indie · Puzzle · Difficult

Poly Bridge
Shared: Puzzle · Indie · Difficult

Kerbal Space Program
Shared: Science · Education · Indie

Patrick's Parabox
Shared: Puzzle · Sokoban · Indie

TIS-100
Shared: Indie · Puzzle · Difficult

Human Resource Machine
Shared: Indie · Puzzle · Education

Cypher
Shared: Indie · Puzzle · Education

Poly Bridge 2
Shared: Puzzle · Difficult · Indie

LIMBO
Shared: Indie · Puzzle · Difficult

Void Stranger
Shared: Puzzle · Indie · Sokoban

Hollow Knight: Silksong
Shared: Indie · Difficult

SHENZHEN I/O
Shared: Puzzle · Indie · Education

7 Billion Humans
Shared: Indie · Puzzle · Education

Zup! S
Shared: Indie · Puzzle · Difficult

Antichamber
Shared: Indie · Puzzle · Difficult

Snakebird
Shared: Indie · Puzzle · Difficult

The Witness
Shared: Puzzle · Indie · Difficult

The Binding of Isaac: Rebirth
Shared: Indie · Difficult

RetroMaze
Shared: Indie · Puzzle · Difficult

Changed
Shared: Puzzle · Difficult · Indie