Games like Minimalist Tower Defense
Games like Minimalist Tower Defense include Plants vs. Zombies GOTY Edition, Kingdom Two Crowns, Bloons TD 6, They Are Billions, and Oxygen Not Included. We matched them by the tags players give Minimalist Tower Defense on Steam (Tower Defense, Strategy, Real Time Tactics, Top-Down, and 2D): closest matches first, and among equally close ones the better-known games.

Plants vs. Zombies GOTY Edition
Shared: Tower Defense · Strategy · 2D

Kingdom Two Crowns
Shared: Tower Defense · Minimalist · Strategy

Bloons TD 6
Shared: Tower Defense · Strategy · Singleplayer

They Are Billions
Shared: Strategy · Tower Defense · Base Building

Oxygen Not Included
Shared: Base Building · 2D · Strategy

Bad North: Jotunn Edition
Shared: Tower Defense · Real Time Tactics · Minimalist

Frostpunk
Shared: Strategy · Post-apocalyptic · Survival

Factorio
Shared: Strategy · Base Building · Resource Management

Creeper World 4
Shared: Tower Defense · Real Time Tactics · Strategy

Kingdom Rush Frontiers - Tower Defense
Shared: Tower Defense · Strategy · 2D

Mindustry
Shared: Tower Defense · Strategy · Base Building

Kingdom Rush - Tower Defense
Shared: Tower Defense · Strategy · 2D

Kingdom Rush Origins - Tower Defense
Shared: Tower Defense · Strategy · 2D

Thronefall
Shared: Tower Defense · Strategy · Minimalist

Creeper World 3: Arc Eternal
Shared: Tower Defense · Strategy · Top-Down

Rogue Tower
Shared: Tower Defense · Strategy · Minimalist

Sheltered
Shared: Strategy · Base Building · Post-apocalyptic

RimWorld
Shared: Strategy · Base Building · Survival

Kingdom: New Lands
Shared: Tower Defense · Base Building · Minimalist

Prison Architect
Shared: Strategy · Base Building · 2D

Rise to Ruins
Shared: Tower Defense · Strategy · Base Building

This War of Mine
Shared: Strategy · Survival · Base Building

GemCraft - Chasing Shadows
Shared: Tower Defense · Strategy · Top-Down

Kingdom Rush 5: Alliance TD
Shared: Tower Defense · Strategy · 2D