Games like Meridian 157: Chapter 2
Games like Meridian 157: Chapter 2 include The Room, The Room Two, The Room 4: Old Sins, There Is No Game: Wrong Dimension, and The Room Three. We matched them by the tags players give Meridian 157: Chapter 2 on Steam (Adventure, Puzzle, Point & Click, Casual, and Hidden Object): closest matches first, and among equally close ones the better-known games.

The Room
Shared: Puzzle · Point & Click · Adventure

The Room Two
Shared: Puzzle · Point & Click · Adventure

The Room 4: Old Sins
Shared: Puzzle · Adventure · Point & Click

There Is No Game: Wrong Dimension
Shared: Puzzle · Adventure · Point & Click

The Room Three
Shared: Puzzle · Adventure · Point & Click

Rusty Lake Paradise
Shared: Puzzle · Point & Click · Adventure

Morphopolis
Shared: Puzzle · Point & Click · Adventure

Fran Bow
Shared: Point & Click · Puzzle · Adventure

Meridian 157: Chapter 1
Shared: Adventure · Puzzle · Point & Click

Servant of the Lake
Shared: Adventure · Puzzle · Point & Click

That's not my Neighbor
Shared: Adventure · Casual · Point & Click

Hidden Folks
Shared: Casual · Hidden Object · Puzzle

Frankenstein: Master of Death
Shared: Point & Click · Puzzle · Adventure

Sally Face - Episode One
Shared: Puzzle · Adventure · Horror

Boxes: Lost Fragments
Shared: Puzzle · Adventure · Point & Click

Gorogoa
Shared: Puzzle · Casual · Point & Click

The House of Da Vinci
Shared: Puzzle · Hidden Object · Point & Click

My Brother Rabbit
Shared: Adventure · Puzzle · Point & Click

Enigmatis 2: The Mists of Ravenwood
Shared: Adventure · Puzzle · Hidden Object

Enigmatis: The Ghosts of Maple Creek
Shared: Adventure · Point & Click · Hidden Object

Samsara Room
Shared: Puzzle · Adventure · Point & Click

Poppy Playtime
Shared: Puzzle · Horror · Adventure

Deponia
Shared: Adventure · Point & Click · Puzzle

Chants of Sennaar
Shared: Adventure · Puzzle · Point & Click