Games like Mercantisle
Games like Mercantisle include Prison Architect, Game Dev Tycoon, Oxygen Not Included, Banished, and RimWorld. We matched them by the tags players give Mercantisle on Steam (Strategy, Simulation, Colony Sim, 2D, and Cartoony): closest matches first, and among equally close ones the better-known games.

Prison Architect
Shared: Simulation · Strategy · Colony Sim

Game Dev Tycoon
Shared: Simulation · Strategy · 2D

Oxygen Not Included
Shared: Colony Sim · 2D · Simulation

Banished
Shared: Strategy · Colony Sim · Simulation

RimWorld
Shared: Colony Sim · Strategy · Simulation

Kingdoms and Castles
Shared: Colony Sim · Simulation · Strategy

Victoria 3
Shared: Strategy · Simulation · Economy

Academia : School Simulator
Shared: Colony Sim · Simulation · Strategy

Manor Lords
Shared: Strategy · Simulation · Colony Sim

Dwarf Fortress
Shared: Colony Sim · Simulation · Strategy

Two Point Museum
Shared: Simulation · Strategy · Cartoony

Unholy Heights
Shared: Strategy · Colony Sim · Cute

Ratopia
Shared: Colony Sim · Strategy · 2D

Empires of the Undergrowth
Shared: Strategy · Simulation · Colony Sim

Against the Storm
Shared: Strategy · Simulation · Colony Sim

Foundation
Shared: Simulation · Strategy · Colony Sim

Cities: Skylines
Shared: Simulation · Strategy · Economy

Production Line : Car factory simulation
Shared: Simulation · Strategy · Economy

Dawn of Man
Shared: Colony Sim · Strategy · Simulation

The Executive - Movie Industry Tycoon
Shared: Simulation · Strategy · 2D

Workers & Resources: Soviet Republic
Shared: Strategy · Simulation · Colony Sim

Democracy 4
Shared: Strategy · Simulation · Economy

Norland
Shared: Strategy · Simulation · Colony Sim

Ostriv
Shared: Strategy · Simulation · Colony Sim